Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis - Wikidata - wikimedia - TriplyDB

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

http://www.wikidata.org/entity/Q34657095

about

EGFR-targeted granzyme B expressed in NK cells enhances natural cytotoxicity and mediates specific killing of tumor cells.A simple and sensitive method for measuring tumor-specific T cell cytotoxicity.Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.Delivery and therapeutic potential of human granzyme B.Ectopically expressed perforin-1 is proapoptotic in tumor cell lines by increasing caspase-3 activity and the nuclear translocation of cytochrome C Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.Efficacy of an adapted granzyme B-based anti-CD30 cytolytic fusion protein against PI-9-positive classical Hodgkin lymphoma cells in a murine model The possible role of granzyme B in the pathogenesis of chronic obstructive pulmonary disease.The battlefield of perforin/granzyme cell death pathways.Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases.Cell death-independent functions of granzymes: hit viruses where it hurts.Controversies in granzyme biology.Blessing or curse? Proteomics in granzyme research.Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice.Impairment of Fas-ligand-caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death.Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins.Human Granzyme B Based Targeted Cytolytic Fusion Proteins.Design of human granzyme B variants resistant to serpin B9

P2860

Q31115054-EDD82302-D47C-48A0-A2AE-253E28365B9B Q33649655-4C9B6C15-A560-4340-ABEE-B7F3478515C7 Q33897989-11634144-1475-4C7D-9A4B-A2B312B41ECC Q34120062-D65C4153-791E-4546-BACA-31F6CB7F9FBC Q34351038-6965A4D8-32EC-4B6F-8BAF-748695A384C1 Q34405882-E834A20C-0C8D-4068-8909-86EF27F0782A Q36736543-8AAAD81A-2488-4B50-B6FB-1D8FC907B810 Q37564741-49D729B0-2FE5-4D4B-9330-D58527A23CEF Q37633282-16580E82-4ECC-403F-B370-C498DCE7F590 Q37859775-171739D8-E5EE-4F1B-8EEF-F9185DD4EF2A Q37895629-123B396E-7854-4CBD-85A1-9A650EE56939 Q38058564-BC2A14E1-7F62-4424-BA2B-FF3576EA5437 Q38200060-1C1CFBA3-1BE5-441A-A842-B1430E4025C6 Q41981686-F1E53B88-DC0E-436C-8F94-15B5B7E870AC Q48191024-5F4C0828-5A5F-435A-9695-92155992C5FA Q53621236-FB241070-4D3E-4C46-AFCC-64833F21AFEE Q55647066-45553CFF-8F48-406B-909E-2D7B9BF62EFD Q57278499-B31AD364-12BE-43A9-9AB0-7743B4190597

P2860

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

http://www.wikidata.org/entity/Q34657095

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@ast

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@en

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@nl

type

label

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@ast

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@en

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@nl

prefLabel

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@ast

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@en

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@nl

P1433

Q34657095-2DBEB882-DB4F-4C9D-8D7A-63CE8DB1683E

P1476

Q34657095-F9C8603E-4877-46BE-9EDC-B89C3FD65693

P2093

Q34657095-6FD7F881-B3A0-437B-B83F-224A529D497B

Q34657095-97C44DFE-CE54-4183-8028-77D20C14D33C

Q34657095-BCC4A419-5FBD-4ED0-ABC6-7FDF6ADDE935

Q34657095-C9AFB744-6B45-407A-AE19-4424324A226F

P2860

Q34657095-0A535B73-DA67-4C40-B953-075BDF318B4B

Q34657095-0F24608F-5941-49A9-BEAC-C3F1B5F9B081

Q34657095-240D3D44-74F1-4DCB-974D-40FBF41D1523

Q34657095-2644761E-B004-4745-B360-6304F15C225C

Q34657095-33229100-8480-42C6-B554-11C1C90766B8

Q34657095-345E29FB-BE5D-4B31-BFB3-9D74EE2CBEB2

Q34657095-3503944F-30D3-458B-A8DF-9B588A3E7761

Q34657095-3E978895-F1AF-4B1B-8C20-CED64869E1B2

Q34657095-55399AF5-1F2C-4B3E-9472-0BEAFAF6CFBE

Q34657095-57CAEFB2-99E0-4AD6-993F-BFB9068820A0

P304

Q34657095-5536A1EB-A424-4174-A986-8AFA9D1609C8

P31

Q34657095-1B42B9F6-707A-489D-A1E4-661E8413DC75

P356

Q34657095-ED92BEA6-5488-4FB2-8DBE-F91B5AC9647E

P407

Q34657095-1507765D-CFE0-44B8-AC2B-F54A1DC6BF79

P433

Q34657095-9E757B33-C63D-4E67-878E-E06B73EAE905

P478

Q34657095-614F21DD-2C1E-4C5A-A9EF-E9B1F993BF80

P577

Q34657095-723FD1DA-9A58-46B9-98A3-7F3121E69FC5

P5875

Q34657095-0DB31C40-B654-478D-AD28-096CCD5E8AA8

P698

Q34657095-D6425FA3-C9F2-4FA8-9F2E-60645B8B4A88

P932

Q34657095-87493FA0-6E7B-4BA9-9B92-35D7CACECC5D

P356

PNAS.0801724105

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Granzyme B delivery via perfor ...... sulfate-dependent endocytosis

@en

P2093

Dieter E Jenne

http://www.w3.org/2001/XMLSchema#string

Edward Fellows

http://www.w3.org/2001/XMLSchema#string

Elisabeth Stegmann

http://www.w3.org/2001/XMLSchema#string

Florian C Kurschus

http://www.w3.org/2001/XMLSchema#string

P2860

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

A common fold mediates vertebrate defense and bacterial attack

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

Structural basis of pore formation by the bacterial toxin pneumolysin

Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis

Calculation of hydrodynamic properties of globular proteins from their atomic-level structure.

Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis.

Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells.

The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities.

P304

13799-13804

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0801724105

http://www.w3.org/2001/XMLSchema#string

P407

P433

37

http://www.w3.org/2001/XMLSchema#string

P478

105

http://www.w3.org/2001/XMLSchema#string

P577

2008-09-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23238488

http://www.w3.org/2001/XMLSchema#string

P698

18772390

http://www.w3.org/2001/XMLSchema#string

P932

2544534

http://www.w3.org/2001/XMLSchema#string