Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis.
about
Human perforin employs different avenues to damage membranesCytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.Perforin rapidly induces plasma membrane phospholipid flip-flopDelivery and therapeutic potential of human granzyme B.Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosisIntracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.Mechanisms of granule-dependent killing.Altered effector function of peripheral cytotoxic cells in COPD.The perforin pore facilitates the delivery of cationic cargos.In the crosshairs: investigating lytic granules by high-resolution microscopy and electrophysiology.The transient pore formed by homologous terminal complement complexes functions as a bidirectional route for the transport of autocrine and paracrine signals across human cell membranes.Anti-perforin neutralizing antibody reduces myocardial injury in viral myocarditis.
P2860
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P2860
Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis.
description
1991 nî lūn-bûn
@nan
1991 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մարտին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Functional size of complement ...... fluorescence microphotolysis.
@ast
Functional size of complement ...... fluorescence microphotolysis.
@en
Functional size of complement ...... fluorescence microphotolysis.
@nl
type
label
Functional size of complement ...... fluorescence microphotolysis.
@ast
Functional size of complement ...... fluorescence microphotolysis.
@en
Functional size of complement ...... fluorescence microphotolysis.
@nl
prefLabel
Functional size of complement ...... fluorescence microphotolysis.
@ast
Functional size of complement ...... fluorescence microphotolysis.
@en
Functional size of complement ...... fluorescence microphotolysis.
@nl
P2093
P1476
Functional size of complement ...... fluorescence microphotolysis.
@en
P2093
P304
P356
10.1016/0005-2736(91)90363-D
P407
P577
1991-03-01T00:00:00Z