Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. - Wikidata - wikimedia - TriplyDB

Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo.

Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo.

http://www.wikidata.org/entity/Q34674963

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Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence Visual activity regulates neural progenitor cells in developing xenopus CNS through musashi1 Synaptic cell adhesion Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease Molecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisal Insulin in the brain: there and back again Impact of postprandial glycaemia on health and prevention of disease Alzheimer's disease and insulin resistance: translating basic science into clinical applications Diabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stress Amyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's disease Postsynaptic distribution of IRSp53 in spiny excitatory and inhibitory neurons Pathways for insulin access to the brain: the role of the microvascular endothelial cell.In vivo time-lapse imaging of cell proliferation and differentiation in the optic tectum of Xenopus laevis tadpoles.Computer aided alignment and quantitative 4D structural plasticity analysis of neurons.Neurogenesis is required for behavioral recovery after injury in the visual system of Xenopus laevis.Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression.Insulin resistance in brain alters dopamine turnover and causes behavioral disorders.Intranasal insulin treatment of an experimental model of moderate traumatic brain injury.Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's disease Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease.Insulin action in brain regulates systemic metabolism and brain function.Co-expression of Argonaute2 Enhances Short Hairpin RNA-induced RNA Interference in Xenopus CNS Neurons In Vivo.High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice.Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes Linking type 2 diabetes and Alzheimer's disease.The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.Anterograde degeneration along the visual pathway after optic nerve injury Input-specific critical periods for experience-dependent plasticity in layer 2/3 pyramidal neurons.Mechanisms and function of dendritic exocytosis.The effects of cardiovascular risk factors on cognitive compromise The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.Insulin resistance predicts medial temporal hypermetabolism in mild cognitive impairment conversion to Alzheimer disease.Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial Insulin is differentially related to cognitive decline and atrophy in Alzheimer's disease and aging.MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling Chronic intermittent ethanol and withdrawal differentially modulate basolateral amygdala AMPA-type glutamate receptor function and trafficking An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.IRS-2 Deficiency impairs NMDA receptor-dependent long-term potentiation.

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P2860

Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo.

http://www.wikidata.org/entity/Q34674963

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Insulin receptor signaling reg ...... and circuit function in vivo.

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Insulin receptor signaling reg ...... and circuit function in vivo.

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Insulin receptor signaling reg ...... and circuit function in vivo.

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Insulin receptor signaling reg ...... and circuit function in vivo.

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Insulin receptor signaling reg ...... and circuit function in vivo.

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Insulin receptor signaling reg ...... and circuit function in vivo.

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J.NEURON.2008.04.014

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Insulin receptor signaling reg ...... and circuit function in vivo.

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Chih-Ming Chen

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Hollis T Cline

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Shu-Ling Chiu

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P2860

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin

Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42

Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases

NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signaling

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD.

Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons.

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