Eukaryotic topoisomerase II. Characterization of enzyme turnover.
about
DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNAEffects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine groupStructure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution.Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187Structure of a topoisomerase II–DNA–nucleotide complex reveals a new control mechanism for ATPase activityReal-time monitoring of protein conformational changes using a nano-mechanical sensorRecovery of the poisoned topoisomerase II for DNA religation: coordinated motion of the cleavage core revealed with the microsecond atomistic simulation.The dynamic interplay between DNA topoisomerases and DNA topology.Natural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIαModulation of gyrase-mediated DNA cleavage and cell killing by ATP.DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsKEukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossoversCleavage of plasmid DNA by eukaryotic topoisomerase II.The use of divalent metal ions by type II topoisomerases.DNA-strand exchange promoted by RecA protein in the absence of ATP: implications for the mechanism of energy transduction in protein-promoted nucleic acid transactions.Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavageSingle-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase IINovel 1-8-bridged chiral quinolones with activity against topoisomerase II: stereospecificity of the eukaryotic enzyme.DNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity.Assembly of spaced chromatin involvement of ATP and DNA topoisomerase activity.Structural similarities between topoisomerases that cleave one or both DNA strands.Coupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism.Depletion of topoisomerase II in isolated nuclei during a glucose-regulated stress responseAbility of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes.The role of DNA bending in type IIA topoisomerase function.DNA topoisomerase II, genotoxicity, and cancerTopoisomerase-specific drug sensitivity in relation to cell cycle progression.The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothingUsing 3'-bridging phosphorothiolates to isolate the forward DNA cleavage reaction of human topoisomerase IIalphaTopoisomerase II: a fitted mechanism for the chromatin landscape.Effects of magnesium and related divalent metal ions in topoisomerase structure and function.Incomplete reversion of double stranded DNA cleavage mediated by Drosophila topoisomerase II: formation of single stranded DNA cleavage complex in the presence of an anti-tumor drug VM26.Alteration of topoisomerase II action is a possible molecular mechanism of HL-60 cell differentiation.Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase.Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.The Dynamic Interplay Between DNA Topoisomerases and DNA Topology.
P2860
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P2860
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
description
1986 nî lūn-bûn
@nan
1986 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@ast
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@en
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@nl
type
label
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@ast
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@en
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@nl
prefLabel
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@ast
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@en
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@nl
P1476
Eukaryotic topoisomerase II. Characterization of enzyme turnover.
@en
P2093
Osheroff N
P304
P407
P577
1986-07-01T00:00:00Z