DNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity.
about
DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNAStructure of a topoisomerase II–DNA–nucleotide complex reveals a new control mechanism for ATPase activityThe DNA binding CXC domain of MSL2 is required for faithful targeting the Dosage Compensation Complex to the X chromosomeE. coli Gyrase Fails to Negatively Supercoil Diaminopurine-Substituted DNA.Coupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism.The role of DNA bending in type IIA topoisomerase function.The why and how of DNA unlinkingDNA topoisomerases: harnessing and constraining energy to govern chromosome topology.The DNA-gate of Bacillus subtilis gyrase is predominantly in the closed conformation during the DNA supercoiling reaction.Distinct regions of the Escherichia coli ParC C-terminal domain are required for substrate discrimination by topoisomerase IV.Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.DNA gyrase with a single catalytic tyrosine can catalyze DNA supercoiling by a nicking-closing mechanism.
P2860
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P2860
DNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
DNA topoisomerase II selects D ...... rather than binding affinity.
@ast
DNA topoisomerase II selects D ...... rather than binding affinity.
@en
type
label
DNA topoisomerase II selects D ...... rather than binding affinity.
@ast
DNA topoisomerase II selects D ...... rather than binding affinity.
@en
prefLabel
DNA topoisomerase II selects D ...... rather than binding affinity.
@ast
DNA topoisomerase II selects D ...... rather than binding affinity.
@en
P2860
P356
P1476
DNA topoisomerase II selects D ...... y rather than binding affinity
@en
P2093
Daniel Herschlag
P2860
P304
P356
10.1093/NAR/GKM335
P407
P577
2007-05-21T00:00:00Z