Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination - Wikidata - wikimedia - TriplyDB

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

http://www.wikidata.org/entity/Q34688242

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RUNX family members are covalently modified and regulated by PIAS1-mediated sumoylation Mdm2 links genotoxic stress and metabolism to p53.Clinicopathological significance and potential drug target of RUNX3 in breast cancer.Stabilization of RNT-1 protein, runt-related transcription factor (RUNX) protein homolog of Caenorhabditis elegans, by oxidative stress through mitogen-activated protein kinase pathway Tumor suppressor function of RUNX3 in breast cancer RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.Identification of RUNX3 as a component of the MST/Hpo signaling pathway.MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.Implicating SCF complexes in organogenesis in Caenorhabditis elegans.RUNX3 is multifunctional in carcinogenesis of multiple solid tumors.MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain.New insights into the inactivation of gastric tumor suppressor RUNX3: the role of H. pylori infection.Oncogenic role of RUNX3 in head and neck cancer.Control of RUNX3 by histone methyltransferases.RUNX family: Regulation and diversification of roles through interacting proteins.MDM2's social network.Clinicopathological significance of RUNX3 gene hypermethylation in hepatocellular carcinoma.Lineage factors and differentiation states in lung cancer progression.Clinicopathological significance and potential drug target of RUNX3 in non-small cell lung cancer: a meta-analysis.Estrogen stimulates the proliferation of human endometrial cancer cells by stabilizing nucleophosmin/B23 (NPM/B23).Triad 1 induces apoptosis by p53 activation.The Many Faces of MDM2 Binding Partners.Regulation of RUNX3 expression and activity Truncated forms of RUNX3 Unlike Full Length Protein Alter Cell Proliferation in a TGF-β Context Dependent Manner.MDM2 binds RUNX3 MDM2 polyubiquitinates RUNX3 Polyubiquitinated RUNX3 translocates to the cytosol Polyubiquitinated RUNX3 is degraded by the proteasome Runx3 and Cell Fate Decisions in Pancreas Cancer.RUNX3 and p53: How Two Tumor Suppressors Cooperate Against Oncogenic Ras?

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P2860

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

http://www.wikidata.org/entity/Q34688242

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@ast

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@en

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@nl

type

label

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@ast

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@en

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@nl

prefLabel

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@ast

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@en

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@nl

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0008-5472.CAN-09-1057

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Cancer Research

P1476

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

@en

P2093

Andre J van Wijnen

http://www.w3.org/2001/XMLSchema#string

Gary S Stein

http://www.w3.org/2001/XMLSchema#string

Heejun Wee

http://www.w3.org/2001/XMLSchema#string

Jiyeon Kim

http://www.w3.org/2001/XMLSchema#string

Jung-Won Lee

http://www.w3.org/2001/XMLSchema#string

Kyeong-Sook Lee

http://www.w3.org/2001/XMLSchema#string

Suk-Chul Bae

http://www.w3.org/2001/XMLSchema#string

Wun-Jae Kim

http://www.w3.org/2001/XMLSchema#string

Xin-Zi Chi

http://www.w3.org/2001/XMLSchema#string

Yong-Hee Lee

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

The RUNX genes: gain or loss of function in cancer

The ubiquitin ligase COP1 is a critical negative regulator of p53

Causal relationship between the loss of RUNX3 expression and gastric cancer

Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

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8111-8119

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scholarly article

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10.1158/0008-5472.CAN-09-1057

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20

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69

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2009-10-06T00:00:00Z

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19808967

http://www.w3.org/2001/XMLSchema#string

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protein ubiquitination

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3059505

http://www.w3.org/2001/XMLSchema#string