The ubiquitin ligase COP1 is a critical negative regulator of p53 - Wikidata - wikimedia - TriplyDB

The ubiquitin ligase COP1 is a critical negative regulator of p53

The ubiquitin ligase COP1 is a critical negative regulator of p53

http://www.wikidata.org/entity/Q28258057

about

Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1 Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53 Identification and characterization of the novel protein CCDC106 that interacts with p53 and promotes its degradation CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1 Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3 HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53 BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53 Acetylation is indispensable for p53 activation FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity p53 Stabilization and accumulation induced by human vaccinia-related kinase 1 Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit CARPs are ubiquitin ligases that promote MDM2-independent p53 and phospho-p53ser20 degradation RNF38 encodes a nuclear ubiquitin protein ligase that modifies p53 Molecular basis of Pirh2-mediated p53 ubiquitylation E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1 Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loop Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1 Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53 Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2 Induction of cullin 7 by DNA damage attenuates p53 function Novel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2 Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 The role of tumor suppressor p53 in the antioxidant defense and metabolism Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemness Function and regulation of cullin-RING ubiquitin ligases Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2 Multiple functions of Jab1 are required for early embryonic development and growth potential in mice

P2860

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P2860

The ubiquitin ligase COP1 is a critical negative regulator of p53

http://www.wikidata.org/entity/Q28258057

description

2004 nî lūn-bûn

@nan

2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

The ubiquitin ligase COP1 is a critical negative regulator of p53

@ast

The ubiquitin ligase COP1 is a critical negative regulator of p53

@en

The ubiquitin ligase COP1 is a critical negative regulator of p53

@nl

type

label

The ubiquitin ligase COP1 is a critical negative regulator of p53

@ast

The ubiquitin ligase COP1 is a critical negative regulator of p53

@en

The ubiquitin ligase COP1 is a critical negative regulator of p53

@nl

prefLabel

The ubiquitin ligase COP1 is a critical negative regulator of p53

@ast

The ubiquitin ligase COP1 is a critical negative regulator of p53

@en

The ubiquitin ligase COP1 is a critical negative regulator of p53

@nl

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The ubiquitin ligase COP1 is a critical negative regulator of p53

@en

P2093

David Arnott

http://www.w3.org/2001/XMLSchema#string

Gretchen D Frantz

http://www.w3.org/2001/XMLSchema#string

Hartmut Koeppen

http://www.w3.org/2001/XMLSchema#string

Harumi Shimizu

http://www.w3.org/2001/XMLSchema#string

Ingrid Wertz

http://www.w3.org/2001/XMLSchema#string

Karen O'Rourke

http://www.w3.org/2001/XMLSchema#string

Patrick Dowd

http://www.w3.org/2001/XMLSchema#string

Vishva M Dixit

http://www.w3.org/2001/XMLSchema#string

P2888

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86-92

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scholarly article

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1116379

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10.1038/NATURE02514

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6987

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429

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2004-05-06T00:00:00Z

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1030067716

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15103385

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