Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha.
about
Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migration.The role of polyamines in protein-dependent hypoxic tolerance of Drosophila.Suppression of exogenous gene expression by spermidine/spermine N1-acetyltransferase 1 (SSAT1) cotransfection.Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.Targeted genes and interacting proteins of hypoxia inducible factor-1.Inactivation of eukaryotic initiation factor 5A (eIF5A) by specific acetylation of its hypusine residue by spermidine/spermine acetyltransferase 1 (SSAT1).Duplication and diversification of the spermidine/spermine N1-acetyltransferase 1 genes in zebrafishAntitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase.CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formationComplex N-acetylation of triethylenetetramine.Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1Hypoxia Inducible Factor 1 Alpha Is Expressed in Germ Cells throughout the Murine Life Cycle.Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.Regulation of cell proliferation by hypoxia-inducible factorsRACK1/Asc1p, a ribosomal node in cellular signaling.Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator.Sirtuin-7 inhibits the activity of hypoxia-inducible factors.Mammalian polyamine metabolism and functionPolyamine catabolism and disease.Hypoxia-inducible factor signaling in pheochromocytoma: turning the rudder in the right direction.Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.Hypoxia-inducible factors--regulation, role and comparative aspects in tumourigenesis.HIF-1α downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic mammalian orthoreovirus.Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes.Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β.A compendium of proteins that interact with HIF-1α.The Kaposi's sarcoma-associated herpesvirus ORF34 protein binds to HIF-1α and causes its degradation via the proteasome pathway.PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia.The regulation effect of ulinastatin on the expression of SSAT2 and AQP4 in myocardial tissue of rats after cardiopulmonary resuscitation.Oncogenic regulation of tumor metabolic reprogramming.Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer.Enhanced polyamine catabolism disturbs hematopoietic lineage commitment and leads to a myeloproliferative disease in mice overexpressing spermidine/spermine N¹-acetyltransferase.Metabolic Regulation of T Cell Immunity.In vitro study of enhanced osteogenesis induced by HIF-1α-transduced bone marrow stem cells.Transcriptional profiling of the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells (HUVECs).
P2860
Q30940749-01022828-4DCD-4CE3-9FF5-A180569028CCQ33389509-AF95BED6-4F06-4138-9C16-48A53C1AC1EBQ33832683-296AC9A5-E07C-44F2-99C2-0C433C521F3CQ34060715-92EDB1AB-AE21-4D23-8645-E5D9F70E232AQ34286796-630E80D6-E408-4E5D-B78B-CE26C62E34C4Q34413595-409DF047-4D04-49FD-A35E-DD6194360B1AQ34552060-1B8821BD-1D60-4971-8C63-FE0B786859F7Q35022155-3B222E96-E69A-4CFC-9D37-9466C6D9B484Q35324189-00147F37-4719-4F8F-BBE5-1393AB75FAD4Q35579534-2C9B854C-41BC-4962-9C4F-4281B69ECC3CQ35838885-D4BC7935-684D-473A-A3ED-76892D808BDBQ36009383-F4749A20-2922-446B-B17D-27E87167A4DCQ36220497-5A6644D1-0247-4439-A505-7145FA541B21Q36381798-7A1C05F9-447D-4932-8C38-83E78F0033F9Q36508167-AA971314-9ABB-433E-8AFF-04030E6D2EEAQ36760384-1D9D9029-B18C-41DC-9E5E-A148032C5B38Q37113086-B39E1578-9B46-42EB-BB84-02F55F5BFEC9Q37175035-DFF6B016-70A5-488E-877B-88D7E8114883Q37365983-ECEA4283-D03B-4C31-8895-C7CFDAF0D352Q37372519-26377B42-62B8-4B00-AB39-DBB1DC4948D3Q37464073-14FE113D-BEBC-4C29-BCF4-427A784B7699Q37772399-849C3D02-6543-428E-8BC4-20BFB79F529DQ37837986-FB5B03AE-589C-42DE-BDA2-2514DD3F3186Q38458133-84112E0F-A38A-4B43-888D-8A37FEDD0408Q38765470-32FA609D-0809-4DE8-90E5-BB11A0FC3D94Q38989123-10668A37-A54E-4B77-9653-00774EA8F583Q39197245-84D72C09-14D5-4099-B2D7-860E3DF0B538Q39230427-BE82AC67-6502-4158-8746-62AF73DDA793Q41883598-2BDFC326-B304-48E4-AB58-F811D05F2AF5Q41963952-06BBA0C2-3761-42AB-9F34-7EBAD6F23733Q42321596-E47F9268-6EE0-438A-9675-104D6247522CQ47160346-51865DC9-12C4-4F0C-A764-8E88A2EF68DDQ48001605-7A4E67E3-79F7-4536-855D-C085981082B3Q50217787-482FDFEC-827F-4CF5-B1F5-AFDAEDCAE95CQ50538332-BB2DB7AC-65E2-4AD6-B156-8516D8493CA3Q52894719-8676898F-6E4E-4E01-A848-C49F0D9BFAB9
P2860
Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha.
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Spermidine/spermine N
@nl
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@ast
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@en
type
label
Spermidine/spermine N
@nl
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@ast
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@en
prefLabel
Spermidine/spermine N
@nl
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@ast
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@en
P2093
P2860
P356
P1476
Spermidine/spermine N(1)-acety ...... and degradation of HIF-1alpha.
@en
P2093
Huafeng Zhang
Jacob B Wesley
Jin H Baek
Karin R McDonald
P2860
P304
33358-33366
P356
10.1074/JBC.M705627200
P407
P577
2007-09-17T00:00:00Z