The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.
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The emerging use of zebrafish to model metabolic diseaseStudying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiologyMetabolic insights from zebrafish genetics, physiology, and chemical biologyThe tumour suppressor LKB1 regulates myelination through mitochondrial metabolism.Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression.Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting.Prolonged hypoxia increases survival even in Zebrafish (Danio rerio) showing cardiac arrhythmiaA post-developmental genetic screen for zebrafish models of inherited liver disease.Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold MorphogenesisAMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma.Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms.Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism.The expanding role of fish models in understanding non-alcoholic fatty liver disease.AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin.Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.The stress polarity pathway: AMPK 'GIV'-es protection against metabolic insults.Insights from model organisms on the functions of the tumor suppressor protein LKB1: zebrafish chips in.The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress.LITTLE FISH, BIG DATA: ZEBRAFISH AS A MODEL FOR CARDIOVASCULAR AND METABOLIC DISEASE.Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish.Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.Synergistic effects of eukaryotic coexpression plasmid carrying LKB1 and FUS1 genes on lung cancer in vitro and in vivo.The tumor suppressor gene lkb1 is essential for glucose homeostasis during zebrafish early development.Impaired caudal fin-fold regeneration in zebrafish deficient for the tumor suppressor Pten.Using zebrafish to model liver diseases-Where do we stand?LKB1 obliterates Snail stability and inhibits pancreatic cancer metastasis in response to metformin treatment.
P2860
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P2860
The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@ast
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@en
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@nl
type
label
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@ast
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@en
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@nl
prefLabel
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@ast
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@en
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@nl
P2093
P2860
P356
P1476
The serine-threonine kinase LK ...... energetic stress in zebrafish.
@en
P2093
Anna-Pavlina G Haramis
Ellen van Rooijen
Hans Clevers
John Zevenhoven
Liqin Wang
Maarten van Lohuizen
Rachel H Giles
Yme U van der Velden
P2860
P304
P356
10.1073/PNAS.1010210108
P407
P577
2011-03-01T00:00:00Z