Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.
about
MicroRNA-regulated viral vectors for gene therapyProgresses towards safe and efficient gene therapy vectorsPromising and delivering gene therapies for vision lossGene therapy of inherited retinal degenerations: prospects and challengesAAV2 delivery of Flt23k intraceptors inhibits murine choroidal neovascularizationAdvancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano SymposiumWhat Is Next for Retinal Gene Therapy?Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating PeptideGene augmentation for adRP mutations in RHO.Human cone visual pigment deletions spare sufficient photoreceptors to warrant gene therapyBlue cone monochromacy: visual function and efficacy outcome measures for clinical trials.Vector platforms for gene therapy of inherited retinopathies.Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind miceGene delivery of a viral anti-inflammatory protein to combat ocular inflammationGene therapy with the caspase activation and recruitment domain reduces the ocular inflammatory responseCapsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and RatVitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsiaControlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells.Retinal Gene Therapy: Current Progress and Future Prospects.Let There Be Light: Gene and Cell Therapy for Blindness.Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus VectorsAAV-mediated transduction and targeting of retinal bipolar cells with improved mGluR6 promoters in rodents and primates.PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina.Adeno-associated Virus Vectors Efficiently Transduce Mouse and Rabbit Sensory Neurons Coinfected with Herpes Simplex Virus 1 following Peripheral Inoculation.Heparan Sulfate Binding Promotes Accumulation of Intravitreally Delivered Adeno-associated Viral Vectors at the Retina for Enhanced Transduction but Weakly Influences Tropism.Proceedings of the First International Optogenetic Therapies for Vision Symposium.Red-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina.Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approachExosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injectionDrug and gene delivery to the back of the eye: from bench to bedside.The Status of RPE65 Gene Therapy Trials: Safety and EfficacyEvaluation of Dose and Safety of AAV7m8 and AAV8BP2 in the Non-Human Primate Retina.Stacking up CRISPR against RNAi for therapeutic gene inhibition.Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells.Gene therapy to rescue retinal degeneration caused by mutations in rhodopsin.Gene and cell-based therapies for inherited retinal disorders: An update.Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy.Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8.
P2860
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P2860
Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@ast
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@en
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@nl
type
label
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@ast
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@en
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@nl
prefLabel
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@ast
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@en
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@nl
P2093
P2860
P1433
P1476
Targeting photoreceptors via i ...... l, capsid-mutated AAV vectors.
@en
P2093
Andrea E Ayala
Christine N Kay
Daniel Kasuga
Frank M Dyka
George V Aslanidi
Jingfen Sun
Kim Van Vliet
Renee C Ryals
Sanford L Boye
P2860
P304
P356
10.1371/JOURNAL.PONE.0062097
P407
P577
2013-04-26T00:00:00Z