High-throughput screen for pharmacoperones of the vasopressin type 2 receptor - Wikidata - wikimedia - TriplyDB

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

http://www.wikidata.org/entity/Q34703957

about

Pharmacological chaperoning: a primer on mechanism and pharmacology Transitioning pharmacoperones to therapeutic use: in vivo proof-of-principle and design of high throughput screens.Chaperoning G protein-coupled receptors: from cell biology to therapeutics Restoration of testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy.Assay strategies for identification of therapeutic leads that target protein trafficking Identification of Potential Pharmacoperones Capable of Rescuing the Functionality of Misfolded Vasopressin 2 Receptor Involved in Nephrogenic Diabetes Insipidus Screening methods for identifying pharmacological chaperones.Pharmacological Chaperones: Beyond Conformational Disorders.Pharmacological Chaperones as Potential Therapeutic Strategies for Misfolded Mutant Vasopressin Receptors.

P2860

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P2860

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

http://www.wikidata.org/entity/Q34703957

description

2013 nî lūn-bûn

@nan

2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@ast

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@en

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@nl

type

label

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@ast

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@en

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@nl

prefLabel

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@ast

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@en

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@nl

P1433

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P1433

Journal of Biomolecular Screening

P1476

High-throughput screen for pharmacoperones of the vasopressin type 2 receptor

@en

P2093

David C Smithson

http://www.w3.org/2001/XMLSchema#string

Emery Smith

http://www.w3.org/2001/XMLSchema#string

Jo Ann Janovick

http://www.w3.org/2001/XMLSchema#string

P Michael Conn

http://www.w3.org/2001/XMLSchema#string

Peter Hodder

http://www.w3.org/2001/XMLSchema#string

P2860

Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugs

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

Trafficking of G-protein-coupled receptors to the plasma membrane: insights for pharmacoperone drugs.

An overview of SR121463, a selective non-peptide vasopressin V(2) receptor antagonist.

Therapeutic rescue of misfolded/mistrafficked mutants: automation-friendly high-throughput assays for identification of pharmacoperone drugs of GPCRs.

Beyond the signal sequence: protein routing in health and disease.

Refolding of misfolded mutant GPCR: post-translational pharmacoperone action in vitro.

G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo.

Drug development and the cellular quality control system.

A bioluminescent-based, HTS-compatible assay to monitor G-protein-coupled receptor modulation of cellular cyclic AMP.

P304

930-937

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scholarly article

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10.1177/1087057113483559

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8

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18

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2013-05-02T00:00:00Z

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236614901

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23640875

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P932

3735853

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