MBD2 contributes to developmental silencing of the human ε-globin gene.
about
Epigenetic modifications and chromosome conformations of the beta globin locus throughout development.MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexesMi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells.Transcriptional mechanisms underlying hemoglobin synthesis.Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny.The role of chromatin modifiers in normal and malignant hematopoiesisAn enhancer haplotype may influence BCL11A expression levels and the response to hydroxyurea in β-thalassemia patients.An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex.
P2860
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P2860
MBD2 contributes to developmental silencing of the human ε-globin gene.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
MBD2 contributes to developmental silencing of the human ε-globin gene.
@ast
MBD2 contributes to developmental silencing of the human ε-globin gene.
@en
MBD2 contributes to developmental silencing of the human ε-globin gene.
@nl
type
label
MBD2 contributes to developmental silencing of the human ε-globin gene.
@ast
MBD2 contributes to developmental silencing of the human ε-globin gene.
@en
MBD2 contributes to developmental silencing of the human ε-globin gene.
@nl
prefLabel
MBD2 contributes to developmental silencing of the human ε-globin gene.
@ast
MBD2 contributes to developmental silencing of the human ε-globin gene.
@en
MBD2 contributes to developmental silencing of the human ε-globin gene.
@nl
P2093
P2860
P1476
MBD2 contributes to developmental silencing of the human ε-globin gene.
@en
P2093
Gordon D Ginder
Jeremy W Rupon
Shou Zhen Wang
Stefanos Labropoulos
P2860
P304
P356
10.1016/J.BCMD.2011.01.001
P577
2011-02-04T00:00:00Z