Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection.
about
Protein C anticoagulant and cytoprotective pathwaysPAR-1 and thrombin: the ties that bind the microenvironment to melanoma metastasisProteases and oxidant stress control organic dust induction of inflammatory gene expression in lung epithelial cellsTissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo.Endothelial cell protein C receptor: a multiliganded and multifunctional receptorAssociation of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: the Athero Gene study.Allosteric modulation of protease-activated receptor signaling.Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIaRole of the protein C receptor in cancer progression.Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection.Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).Inactivation of factor VIIa by antithrombin in vitro, ex vivo and in vivo: role of tissue factor and endothelial cell protein C receptor.Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular PatternsEndothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa.Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function.Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER).Heterozygous congenital Factor VII deficiency with the 9729del4 mutation, associated with severe spontaneous intracranial bleeding in an adolescent maleMechanisms of anticoagulant and cytoprotective actions of the protein C pathway.Doxycycline directly targets PAR1 to suppress tumor progression.Endothelium--role in regulation of coagulation and inflammation.The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.Rho GTPases in the regulation of pulmonary vascular barrier function.A novel protein C-factor VII chimera provides new insights into the structural requirements for cytoprotective PAR1 signaling.Targeting clotting proteins in cancer therapy - progress and challenges.Endothelial cell protein C receptor promotes MGC803 gastric cancer cells proliferation and migration by activating ERK1/2.Proteinases, Their Extracellular Targets, and Inflammatory Signaling.Endothelial cell protein C receptor opposes mesothelioma growth driven by tissue factor.Homeostatic effects of coagulation protease-dependent signaling and protease activated receptors.The role of recombinant activated factor VII in the haematological management of elective orthopaedic surgery in haemophilia A patients with inhibitors.Endothelial protein C receptor is required for tissue factor ternary complex signaling in the mouse.An activated factor VII variant with enhanced tissue factor-independent activity speeds wound healing in a mouse hemophilia B model.Anticoagulation increases alveolar hemorrhage in mice infected with influenza A.Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study.Proteinase-activated receptor-1 and immunomodulatory effects of a PAR1-activating peptide in a mouse model of prostatitis.Glycosylation of tissue factor is not essential for its transport or functions.Rivaroxaban does not increase hemorrhage after thrombolysis in experimental ischemic stroke.The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.Safety and efficacy of recombinant activated factor VII for long-term secondary prophylaxis in a haemophilia boy with high-titre inhibitors.PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury.
P2860
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P2860
Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Factor VIIa bound to endotheli ...... naling and barrier protection.
@ast
Factor VIIa bound to endotheli ...... naling and barrier protection.
@en
Factor VIIa bound to endotheli ...... naling and barrier protection.
@nl
type
label
Factor VIIa bound to endotheli ...... naling and barrier protection.
@ast
Factor VIIa bound to endotheli ...... naling and barrier protection.
@en
Factor VIIa bound to endotheli ...... naling and barrier protection.
@nl
prefLabel
Factor VIIa bound to endotheli ...... naling and barrier protection.
@ast
Factor VIIa bound to endotheli ...... naling and barrier protection.
@en
Factor VIIa bound to endotheli ...... naling and barrier protection.
@nl
P2093
P2860
P1433
P1476
Factor VIIa bound to endotheli ...... naling and barrier protection.
@en
P2093
Charles T Esmon
Curtis A Clark
Hema Kothari
L Vijaya Mohan Rao
Prosenjit Sen
Ramakrishnan Gopalakrishnan
Shiva Keshava
Usha R Pendurthi
P2860
P304
P356
10.1182/BLOOD-2010-09-310706
P407
P577
2011-01-20T00:00:00Z