The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.
about
Endothelial cell protein C receptor: a multiliganded and multifunctional receptorHeterozygous congenital Factor VII deficiency with the 9729del4 mutation, associated with severe spontaneous intracranial bleeding in an adolescent maleOne amino acid in mouse activated factor VII defines its endothelial protein C receptor (EPCR) binding and modulates its EPCR-dependent hemostatic activity in vivo.The role of recombinant activated factor VII in the haematological management of elective orthopaedic surgery in haemophilia A patients with inhibitors.Blockade of endothelial cell protein C receptor augments factor VIIa hemostatic effect in hemophilia treatment.In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug.Kinetic analysis and binding studies of a new recombinant human factor VIIa for treatment of haemophilia.Safety and dose-dependency of eptacog beta (activated) in a dose escalation study of non-bleeding congenital haemophilia A or B patients, with or without inhibitors.
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Q34136982-63D78D0F-B4C3-4F3A-B35E-ECB50F9B5020Q36921588-5D520F24-B0F7-4604-8BA3-EBE6312312E0Q39051233-353A24CD-80C8-4799-94CC-B84AC94A9EC4Q39420691-C037EAA3-CAE1-4AAC-895D-3E82E6D6E269Q42432059-881E3CEC-4A9A-4D2E-A3C9-8DFC72F648CFQ45855083-9CD79FB3-6C0B-4A8D-BFDE-056EBDFC55A9Q45863062-CDB74392-CD22-4506-8D94-3A768729FDEDQ45872851-7AFC742F-AE39-4F68-B1A4-4917DAF48F4F
P2860
The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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2014年论文
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name
The endothelial protein C rece ...... on in hemophilic mice in vivo.
@en
The endothelial protein C rece ...... on in hemophilic mice in vivo.
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type
label
The endothelial protein C rece ...... on in hemophilic mice in vivo.
@en
The endothelial protein C rece ...... on in hemophilic mice in vivo.
@nl
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The endothelial protein C rece ...... on in hemophilic mice in vivo.
@en
The endothelial protein C rece ...... on in hemophilic mice in vivo.
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P2093
P2860
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The endothelial protein C rece ...... on in hemophilic mice in vivo.
@en
P2093
Armida Faella
Lacramioara Ivanciu
Oscar A Marcos-Contreras
Paris Margaritis
P2860
P304
P356
10.1182/BLOOD-2014-04-567297
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P577
2014-06-23T00:00:00Z