Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair
about
Update of the human and mouse Fanconi anemia genesCoordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal.APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2The Fanconi anemia pathway in replication stress and DNA crosslink repair.The Fanconi anemia ID2 complex: dueling saxes at the crossroads.ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.The identification of FANCD2 DNA binding domains reveals nuclear localization sequences.FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.Novel FANCI mutations in Fanconi anemia with VACTERL association.
P2860
Q26776461-9682C722-40DF-4C0F-86CB-D4941A79492BQ35054036-EB8CA300-E9DC-422D-B046-E9C51CDEDBE2Q35130203-C06C3259-3488-4FE2-AE4C-54BFFE4528FAQ35796778-4687ED0D-0498-44DA-B53F-A205668C96A5Q38022544-5F7FCC33-F83B-4A2B-A003-5FCADDA3663EQ38285213-458350CB-53FE-4628-B1CE-5147A187F21CQ38890805-0C9E4EE8-F850-4582-A568-60F6C303804BQ47111729-210D5AA9-EA29-4D12-A1B4-14BB1F746177Q47142336-9113CD47-B72E-45A4-917A-8B0F30AB17F2Q53269676-0D59EACE-71EA-4C70-A04F-7FC8644D6BAC
P2860
Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Patient-derived C-terminal mut ...... E motif function in DNA repair
@ast
Patient-derived C-terminal mut ...... E motif function in DNA repair
@en
Patient-derived C-terminal mut ...... E motif function in DNA repair
@nl
type
label
Patient-derived C-terminal mut ...... E motif function in DNA repair
@ast
Patient-derived C-terminal mut ...... E motif function in DNA repair
@en
Patient-derived C-terminal mut ...... E motif function in DNA repair
@nl
prefLabel
Patient-derived C-terminal mut ...... E motif function in DNA repair
@ast
Patient-derived C-terminal mut ...... E motif function in DNA repair
@en
Patient-derived C-terminal mut ...... E motif function in DNA repair
@nl
P2093
P2860
P1433
P1476
Patient-derived C-terminal mut ...... E motif function in DNA repair
@en
P2093
Detlev Schindler
Helmut Hanenberg
Tony T Huang
Xiomaris M Cotto-Rios
P2860
P304
P356
10.1182/BLOOD-2010-07-295758
P407
P577
2010-10-22T00:00:00Z