ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.
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Interplay between Fanconi anemia and homologous recombination pathways in genome integrityRole of Deubiquitinating Enzymes in DNA RepairReplication stress: getting back on trackReplication stress in Mammalian cells and its consequences for mitosisRescue from replication stress during mitosis.FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2Replication Protein A (RPA) deficiency activates the Fanconi anemia DNA repair pathway.Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.Natural history and management of Fanconi anemia patients with head and neck cancer: A 10-year follow-up.Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathwayThe Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia.FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.Probing the Spatial Organization of Molecular Complexes Using Triple-Pair-Correlation.FANCJ is essential to maintain microsatellite structure genome-wide during replication stress.Molecular Pathways: Targeting ATR in Cancer TherapyThe essential kinase ATR: ensuring faithful duplication of a challenging genome.DNA replication stress: from molecular mechanisms to human disease.FANCD2 limits replication stress and genome instability in cells lacking BRCA2.Order from clutter: selective interactions at mammalian replication origins.FANCD2 Facilitates Replication through Common Fragile Sites.Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development.Nuclear DNA Replication in Trypanosomatids: There Are No Easy Methods for Solving Difficult Problems.Emerging functions of the Fanconi anemia pathway at a glance.Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex.FANCD2 and DNA Damage.FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors.Fanconi Anemia Signaling and Cancer.53BP1 Mediates ATR-Chk1 Signaling And Protects Replication Forks Under Conditions Of Replication Stress.The evolving role of DNA inter-strand crosslinks in chemotherapy.PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading.Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
P2860
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P2860
ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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name
ATR-mediated phosphorylation o ...... esponse to replication stress.
@en
type
label
ATR-mediated phosphorylation o ...... esponse to replication stress.
@en
prefLabel
ATR-mediated phosphorylation o ...... esponse to replication stress.
@en
P2093
P2860
P50
P1433
P1476
ATR-mediated phosphorylation o ...... response to replication stress
@en
P2093
Prasad V Jallepalli
Robert J Sims
Sarah B Crist
Tony T Huang
Yandong Yin
Yu-Hung Chen
P2860
P304
P356
10.1016/J.MOLCEL.2015.02.031
P577
2015-04-02T00:00:00Z