The metabolism and toxicity of quinones, quinonimines, quinone methides, and quinone-thioethers.
about
Cytotoxicity mechanism of two naphthoquinones (menadione and plumbagin) in Saccharomyces cerevisiaeFormation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective EffectsMoles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell CultureIdentification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis.Physicochemical drug properties associated with in vivo toxicological outcomes: a review.Pyrroloquinoline-quinone and its versatile roles in biological processes.Protein tyrosine phosphatases as potential therapeutic targets.Quinone Methide Bioactivation Pathway: Contribution to Toxicity and/or Cytoprotection?Lessons from a BACE1 inhibitor trial: off-site but not off base.Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress.The SoxRS response of Escherichia coli is directly activated by redox-cycling drugs rather than by superoxideQuinone-induced protein handling changes: implications for major protein handling systems in quinone-mediated toxicitySynthetic 1,4-pyran naphthoquinones are potent inhibitors of dengue virus replication.Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.4-Amino-2-chlorophenol: Comparative in vitro nephrotoxicity and mechanisms of bioactivationElectrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions.Phytochemical investigation of Aloe pulcherrima roots and evaluation for its antibacterial and antiplasmodial activitiesMetabolic map and bioactivation of the anti-tumour drug noscapine.Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2.Influence of structural and functional modifications of selected genotoxic carcinogens on metabolism and mutagenicity - a review.Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery.RNA-sequencing quantification of hepatic ontogeny of phase-I enzymes in mice.Semiquinone radicals from oxygenated polychlorinated biphenyls: electron paramagnetic resonance studies.Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells.Effects of combined radiofrequency radiation exposure on levels of reactive oxygen species in neuronal cellsDeleterious effects of reactive metabolites.The carcinogenic effects of benzoquinones produced by the flour beetle.Metabolic activation in drug-induced liver injury.Cytotoxic and antioxidant marine prenylated quinones and hydroquinones.A review on the role of quinones in renal disorders.Cytotoxic Compounds from Aloe megalacantha.The role of urinary pH in o-phenylphenol-induced cytotoxicity and chromosomal damage in the bladders of F344 rats.Cytotoxicity of luteolin in primary rat hepatocytes: the role of CYP3A-mediated ortho-benzoquinone metabolite formation and glutathione depletion.Cytotoxic quinones from the roots of Aloe dawei.Traditional uses, phytochemistry and pharmacology of the medicinal species of the genus Cordia (Boraginaceae).Role of glutathione in augmenting the anticancer activity of pyrroloquinoline quinone (PQQ).Ferrocenyl quinone methides as strong antiproliferative agents: formation by metabolic and chemical oxidation of ferrocenyl phenols.Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives.Evidence for Tissue Toxicity in BALB/c Exposed to a Long-Term Treatment with Oxiranes Compared to Meglumine Antimoniate
P2860
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P2860
The metabolism and toxicity of quinones, quinonimines, quinone methides, and quinone-thioethers.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@ast
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@en
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@nl
type
label
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@ast
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@en
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@nl
prefLabel
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@ast
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@en
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@nl
P356
P1476
The metabolism and toxicity of ...... hides, and quinone-thioethers.
@en
P2093
Douglas C Jones
Terrence J Monks
P304
P356
10.2174/1389200023337388
P407
P577
2002-08-01T00:00:00Z