Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics. - Wikidata - wikimedia - TriplyDB

Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics.

Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics.

http://www.wikidata.org/entity/Q34717853

about

Illumination of parainfluenza virus infection and transmission in living animals reveals a tissue-specific dichotomy CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium Anticancer oncolytic activity of respiratory syncytial virus.Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus.Recombinant respiratory syncytial viruses lacking the C-terminal third of the attachment (G) protein are immunogenic and attenuated in vivo and in vitro.Progress in the development of human parainfluenza virus vaccines Animal pneumoviruses: molecular genetics and pathogenesis.α-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors A single intranasal inoculation with a paramyxovirus-vectored vaccine protects guinea pigs against a lethal-dose Ebola virus challenge New directions in vaccine research.The quest for an efficacious antiviral for respiratory syncytial virus.Recovery of human metapneumovirus genetic lineages a and B from cloned cDNA.Antisense approaches for inhibiting respiratory syncytial virus.New generation live vaccines against human respiratory syncytial virus designed by reverse genetics.Cross-immunity between strains explains the dynamical pattern of paramyxoviruses Evaluation of two chimeric bovine-human parainfluenza virus type 3 vaccines in infants and young children Characterization of recombinant respiratory syncytial viruses with the region responsible for type 2 T-cell responses and pulmonary eosinophilia deleted from the attachment (G) protein.Live-attenuated respiratory syncytial virus vaccines.A paramyxovirus-vectored intranasal vaccine against Ebola virus is immunogenic in vector-immune animals Codon substitution mutations at two positions in the L polymerase protein of human parainfluenza virus type 1 yield viruses with a spectrum of attenuation in vivo and increased phenotypic stability in vitro.Generation of recombinant human parainfluenza virus type 1 vaccine candidates by importation of temperature-sensitive and attenuating mutations from heterologous paramyxoviruses.Sendai virus as a backbone for vaccines against RSV and other human paramyxoviruses trans-Complementation allows recovery of human respiratory syncytial viruses that are infectious but deficient in cell-to-cell transmission.Respiratory syncytial virus vaccine: Is it coming?Structural, antigenic and immunogenic features of respiratory syncytial virus glycoproteins relevant for vaccine development.Parainfluenza virus type 3 expressing the native or soluble fusion (F) Protein of Respiratory Syncytial Virus (RSV) confers protection from RSV infection in African green monkeys.Virulence of Newcastle disease virus: what is known so far?The viral replication complex is associated with the virulence of Newcastle disease virus Vaccines

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P2860

Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics.

http://www.wikidata.org/entity/Q34717853

description

2002 nî lūn-bûn

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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Live-attenuated virus vaccines ...... lications of reverse genetics.

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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Journal of Clinical Investigation

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Live-attenuated virus vaccines ...... lications of reverse genetics.

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P2093

Brian R Murphy

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Peter L Collins

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P2860

Replacement of the F and G proteins of respiratory syncytial virus (RSV) subgroup A with those of subgroup B generates chimeric live attenuated RSV subgroup B vaccine candidates.

Bovine parainfluenza virus type 3 (BPIV3) fusion and hemagglutinin-neuraminidase glycoproteins make an important contribution to the restricted replication of BPIV3 in primates.

Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees

Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity.

Identification of mutations contributing to the temperature-sensitive, cold-adapted, and attenuation phenotypes of the live-attenuated cold-passage 45 (cp45) human parainfluenza virus 3 candidate vaccine.

Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees.

Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for va

Paramyxovirus reverse genetics is coming of age.

Rational design of live-attenuated recombinant vaccine virus for human respiratory syncytial virus by reverse genetics.

A recombinant human parainfluenza virus type 3 (PIV3) in which the nucleocapsid N protein has been replaced by that of bovine PIV3 is attenuated in primates.

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21-27

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scholarly article

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10.1172/JCI0216077

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1

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110

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2002-07-01T00:00:00Z

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12093883

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attenuated vaccine

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151040

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