about
The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancersSrc kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasmHoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalizationA Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesisInsertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomasMN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in miceStem Cell Modeling of Core Binding Factor Acute Myeloid LeukemiaCytogenetic and molecular abnormalities in chronic myelomonocytic leukemiaInterplay between Transcription Factors and the Epigenome: Insight from the Role of RUNX1 in LeukemiaCore Binding Factor Acute Myeloid Leukemia: New Prognostic Categories and Therapeutic OpportunitiesIsoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivoEts-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cellsThe RUNX genes: gain or loss of function in cancerThe Kasumi-1 cell line: a t(8;21)-kit mutant model for acute myeloid leukemiaCbfbeta interacts with Runx2 and has a critical role in bone developmentMutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunitAlveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial CellsAccelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1Imaging findings in recurrent extramedullary leukaemias.CBFbeta is critical for AML1-ETO and TEL-AML1 activity.Runx family genes in a cartilaginous fish, the elephant shark (Callorhinchus milii).PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesisA Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.Human phenotypes associated with GATA-1 mutations.Two novel RUNX1 mutations in a patient with congenital thrombocytopenia that evolved into a high grade myelodysplastic syndromeRUNX family members are covalently modified and regulated by PIAS1-mediated sumoylationA Novel Variant t(1;22) Translocation - ins(22;1)(q13;p13p31) - in a Child with Acute Megakaryoblastic LeukemiaNew Financial and Research Models for Pediatric Orphan Drug Development - Focus on the NCATS TRND ProgramHematopoietic stem cells and retroviral infection.Cbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11.Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis.Runx1 is a tumor suppressor gene in the mouse gastrointestinal tract.Comprehensive mutational profiling of core binding factor acute myeloid leukemia.Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemiaRunx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cellsPoint mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer.Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin.Expression analysis of Runx3 and other Runx family members during Xenopus development
P2860
Q21260410-75FA12D4-3D44-4D4F-B566-7A2A15DC09ACQ24297348-2B8B3456-CAD2-4B2F-9667-35FB101940DBQ24603527-9D8322E5-217C-401E-845E-C21006B52059Q24634134-D9321358-DC01-4C6F-8BE6-4C49208501DBQ24657196-D68949B0-A9F5-4FCD-B4F6-B079ED9AB0BCQ24669642-67E3A4B2-9A95-4400-AEA3-E6A2A25A2F6BQ26765858-357B3274-C9BD-40DE-A8C1-91DD3C44DB67Q26768600-619BC8A0-6716-46B4-AFF4-7DC0DA61791AQ26781526-F907D74C-4D73-45AD-8658-C1AA0AD6681EQ26863756-C071EB45-6F77-4111-842F-FB6F756642EAQ27307661-9895C3B0-9732-45F2-9A13-1FCD6A40ED7BQ28201653-760A76F1-B4D8-4ABC-B9C3-8F3257B8511DQ28237966-767F9DD4-2429-4646-96CA-EDC95B2939B2Q28247901-CBBC4E39-930A-45A0-BF2F-C46E62881141Q28300267-6CCF3CE5-3202-4590-B462-196947966B0DQ28586662-5F20E214-FC33-4315-A4F7-8C47C01EBBC1Q28590672-E41ED5C5-2299-46D7-8D70-32D0649115CFQ30275003-3484E7FF-F34C-48A7-9252-18C6995DB24DQ30432285-013D60DB-150E-4AC4-BEE5-9FF9384CED2FQ30436744-CA676E99-8E8C-4E8E-916C-F41FD8D1A86CQ30439864-F2734F4A-A13E-48E8-BDFB-B822D533A9ABQ31156994-3693F1F5-CD4E-4C32-89E2-2A2C2E72FB7CQ32884406-25EE5698-3222-44DA-BA4C-74CEC91F32B9Q32884462-74890397-6EF9-4D8F-ABBA-A4F02795E155Q33381670-8821E459-AFE9-493B-9030-4010C9F8EF21Q33422165-A208F939-CC07-4504-B524-B27AE331BD08Q33555071-055FB147-B342-495D-97EA-B7072A0D3C04Q33601643-6C00047F-A294-4FD0-BCA4-7C42E7776BE6Q33621814-A195AF91-CA70-4146-9ACE-9DA835CAC06EQ33677922-5700D8EC-C7A3-4C5D-98D9-BF244ADBBA73Q33680301-9BCF4BCB-AEE6-4BD2-9C53-2BE2BF3DE823Q33697376-50788949-AC29-477D-B304-71F2188F94D6Q33711292-F1D390C9-F35C-439D-B4B6-1A3F699A8843Q33758306-0F0AB17E-537E-48EE-ACA7-DB1A499BC3A6Q33774508-B6C82AD4-8E46-459F-BE1F-0F7B926B4E38Q33787937-71D0BAEC-EDF4-4F5A-A08B-06C2B0830327Q33821606-B8140DFF-8E09-4737-BFA0-7FCF8883D25BQ33823421-E9F35427-2386-4B65-9587-99FA3B5D25FCQ33826525-8D12B227-1ED8-4F10-9619-A96F097868BDQ33957215-10EF49D3-04BA-444D-92DC-7DABEC27F45D
P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Core-binding factors in haematopoiesis and leukaemia.
@ast
Core-binding factors in haematopoiesis and leukaemia.
@en
Core-binding factors in haematopoiesis and leukaemia.
@nl
type
label
Core-binding factors in haematopoiesis and leukaemia.
@ast
Core-binding factors in haematopoiesis and leukaemia.
@en
Core-binding factors in haematopoiesis and leukaemia.
@nl
prefLabel
Core-binding factors in haematopoiesis and leukaemia.
@ast
Core-binding factors in haematopoiesis and leukaemia.
@en
Core-binding factors in haematopoiesis and leukaemia.
@nl
P356
P1476
Core-binding factors in haematopoiesis and leukaemia.
@en
P2093
D Gary Gilliland
Nancy A Speck
P2888
P304
P356
10.1038/NRC840
P407
P577
2002-07-01T00:00:00Z
P6179
1053102883