Alpha beta and gamma delta T cells can share a late common precursor.
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Human Peripheral CD4(+) Vδ1(+) γδT Cells Can Develop into αβT CellsHuman alpha beta and gamma delta thymocyte development: TCR gene rearrangements, intracellular TCR beta expression, and gamma delta developmental potential--differences between men and miceSix-of-the-best: unique contributions of γδ T cells to immunologyGerminal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cellsThe TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specificationAlternative splicing of rearranged T cell receptor delta sequences to the constant region of the alpha locus.Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers.Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice.Positive and negative regulation of V(D)J recombination by the E2A proteins.Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells.Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling.The biological activity of natural and mutant pTalpha allelesDevelopmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancerIdentification of a DNA segment exhibiting rearrangement modifying effects upon transgenic delta-deleting elements.The common cytokine receptor gamma chain controls survival of gamma/delta T cells.Recent insights into the signals that control alphabeta/gammadelta-lineage fate.Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytesKinetics of T cell receptor beta, gamma, and delta rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) Pro-T thymocytes.Development and selection of gammadelta T cells.In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis.An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locusTowards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.A delta T-cell receptor deleting element transgenic reporter construct is rearranged in alpha beta but not gamma delta T-cell lineagesMolecular mechanisms of pre-T cell receptor-induced survival.Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.T-cell fate.Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment.Gammadelta T-cell precursor-derived CD4- CD8- alphabeta T cells retain gammadelta cell function.The preTCR-dependent DN3 to DP transition requires Notch signaling, is improved by CXCL12 signaling and is inhibited by IL-7 signaling.TCR-beta chains derived from peripheral gammadelta T cells can take part in alphabeta T-cell development.Immature thymocytes that fail to express TCRbeta and/or TCRgamma delta proteins die by apoptotic cell death in the CD44(-)CD25(-) (DN4) subset.Defining the specific physiological requirements for c-Myc in T cell development.Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
P2860
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P2860
Alpha beta and gamma delta T cells can share a late common precursor.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Alpha beta and gamma delta T cells can share a late common precursor.
@ast
Alpha beta and gamma delta T cells can share a late common precursor.
@en
Alpha beta and gamma delta T cells can share a late common precursor.
@nl
type
label
Alpha beta and gamma delta T cells can share a late common precursor.
@ast
Alpha beta and gamma delta T cells can share a late common precursor.
@en
Alpha beta and gamma delta T cells can share a late common precursor.
@nl
prefLabel
Alpha beta and gamma delta T cells can share a late common precursor.
@ast
Alpha beta and gamma delta T cells can share a late common precursor.
@en
Alpha beta and gamma delta T cells can share a late common precursor.
@nl
P2093
P1433
P1476
Alpha beta and gamma delta T cells can share a late common precursor.
@en
P2093
P304
P356
10.1016/S0960-9822(95)00131-X
P407
P577
1995-06-01T00:00:00Z