Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
about
SMAR1 and Cux/CDP modulate chromatin and act as negative regulators of the TCRbeta enhancer (Ebeta)Recombination signal sequence-associated restriction on TCRdelta gene rearrangement affects the development of tissue-specific gammadelta T cells.TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexesIntermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends.ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.T cell receptor (TCR) alpha/delta locus enhancer identity and position are critical for the assembly of TCR delta and alpha variable region genes.The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors.Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segmentsIntercellular Protein Transfer from Thymocytes to Thymic Epithelial CellsThe interleukin 7 receptor is required for T cell receptor gamma locus accessibility to the V(D)J recombinase.The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo.Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell developmentTCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex.Developmentally regulated expression of the transmembrane adaptor protein trim in fetal and adult T cells.TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome.A pTalpha-negative subpopulation of CD25+ TN thymocytes revealed by a transgenic marker.Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus.
P2860
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P2860
Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Developmental regulation of V
@nl
Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
@en
type
label
Developmental regulation of V
@nl
Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
@en
prefLabel
Developmental regulation of V
@nl
Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
@en
P2093
P2860
P1476
Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.
@en
P2093
Hernandez-Munain C
Krangel MS
Roberts JL
P2860
P304
P356
10.1111/J.1600-065X.1998.TB01236.X
P577
1998-10-01T00:00:00Z