Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor. - Wikidata - wikimedia - TriplyDB

Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.

Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.

http://www.wikidata.org/entity/Q34719875

about

Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I Design of an Active Ultrastable Single-chain Insulin Analog: SYNTHESIS, STRUCTURE, AND THERAPEUTIC IMPLICATIONS Design of an Insulin Analog with Enhanced Receptor Binding Selectivity: RATIONALE, STRUCTURE, AND THERAPEUTIC IMPLICATIONS Structural and Biological Properties of the Drosophila Insulin-like Peptide 5 Show Evolutionary Conservation Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design.Insulin/receptor binding: the last piece of the puzzle? What recent progress on the structure of the insulin/receptor complex tells us (or not) about negative cooperativity and activation.A comparative structural bioinformatics analysis of the insulin receptor family ectodomain based on phylogenetic information.Minireview: Tipping the balance: ligand-independent activation of steroid receptors.Will targeting insulin growth factor help us or hurt us?: An oncologist's perspective The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1).Update on human health concerns of recombinant bovine somatotropin use in dairy cows.Ligand-Binding Affinity at the Insulin Receptor Isoform-A and Subsequent IR-A Tyrosine Phosphorylation Kinetics are Important Determinants of Mitogenic Biological Outcomes.Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A Elucidating the Activation Mechanism of the Insulin-Family Proteins with Molecular Dynamics Simulations.Age-dependent reduction of the PI3K regulatory subunit p85α suppresses pancreatic acinar cell proliferation The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer.Theoretical and computational studies of peptides and receptors of the insulin family.A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II.Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins.Type I Interferons, Autophagy and Host Metabolism in Leprosy.[Research progress on the relationship between insulin-like growth factor-I and lung cancer].

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P2860

Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.

http://www.wikidata.org/entity/Q34719875

description

2007 nî lūn-bûn

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2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Structural basis for the lower ...... tors for the insulin receptor.

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Journal of Biological Chemistry

P1476

Structural basis for the lower ...... tors for the insulin receptor.

@en

P2093

Asser S Andersen

http://www.w3.org/2001/XMLSchema#string

Birgit Klaproth

http://www.w3.org/2001/XMLSchema#string

Kerrie A McNeil

http://www.w3.org/2001/XMLSchema#string

Lisbeth Gauguin

http://www.w3.org/2001/XMLSchema#string

Waseem Sajid

http://www.w3.org/2001/XMLSchema#string

P2860

The disulphide bonds of insulin

The insulin-like growth factor (IGF)binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysis

Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor

Insulin and its receptor: structure, function and evolution.

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

Structure and function of the type 1 insulin-like growth factor receptor.

Structural biology of insulin and IGF1 receptors: implications for drug design.

Insulin interactions with its receptors: experimental evidence for negative cooperativity.

Insulin-like growth factors I and II.

Sequence of the human insulin gene.

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2604-2613

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scholarly article

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10.1074/JBC.M709220200

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5

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283

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Pierre De Meyts

Briony E. Forbes

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2007-11-29T00:00:00Z

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18048361

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