Farnesoid X receptor, overexpressed in pancreatic cancer with lymph node metastasis promotes cell migration and invasion.
about
Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization.Correlated high expression of FXR and Sp1 in cancer cells confers a poor prognosis for pancreatic cancer: A study based on TCGA and tissue microarrayDownregulation of nuclear receptor FXR is associated with multiple malignant clinicopathological characteristics in human hepatocellular carcinoma.Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs.Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts.Discovery of Transcriptional Targets Regulated by Nuclear Receptors Using a Probabilistic Graphical ModelGuggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression.Overexpression of farnesoid X receptor in small airways contributes to epithelial to mesenchymal transition and COX-2 expression in chronic obstructive pulmonary disease.Metastasis suppressors in breast cancers: mechanistic insights and clinical potentialPotential therapeutic targets of Guggulsterone in cancerGuggulsterone enhances antitumor activity of gemcitabine in gallbladder cancer cells through suppression of NF-κB.Clinical significance of farnesoid X receptor expression in thyroid neoplasia.SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound.Guggulsterone and Its Role in Chronic Diseases.Inhibition of SCAMP1 suppresses cell migration and invasion in human pancreatic and gallbladder cancer cells.Waltonitone inhibits proliferation of hepatoma cells and tumorigenesis via FXR-miR-22-CCNA2 signaling pathwayGuggulsterone induces apoptosis of human hepatocellular carcinoma cells through intrinsic mitochondrial pathway.Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer.Synthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptorsEnhanced expression of farnesoid X receptor in human hepatocellular carcinoma.Inhibition of Leydig tumor growth by farnesoid X receptor activation: the in vitro and in vivo basis for a novel therapeutic strategy.Current and future roles of mucins in cholangiocarcinoma-recent evidences for a possible interplay with bile acids
P2860
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P2860
Farnesoid X receptor, overexpressed in pancreatic cancer with lymph node metastasis promotes cell migration and invasion.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@ast
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@en
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@nl
type
label
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@ast
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@en
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@nl
prefLabel
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@ast
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@en
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@nl
P2093
P2860
P356
P1476
Farnesoid X receptor, overexpr ...... s cell migration and invasion.
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.2011.37
P407
P577
2011-03-01T00:00:00Z
P5875
P6179
1012715182