Activation of phenylalanine hydroxylase by phenylalanine does not require binding in the active site
about
Structural insights into the regulation of aromatic amino acid hydroxylationThe Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers.First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramerIdentification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase.Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation.Structural basis for ligand-dependent dimerization of phenylalanine hydroxylase regulatory domain.PKU mutation p.G46S prevents the stereospecific binding of l-phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain.The regulatory domain of human tryptophan hydroxylase 1 forms a stable dimerThermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.Towards the identification of the allosteric Phe-binding site in phenylalanine hydroxylase.
P2860
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P2860
Activation of phenylalanine hydroxylase by phenylalanine does not require binding in the active site
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Activation of phenylalanine hy ...... ire binding in the active site
@ast
Activation of phenylalanine hy ...... ire binding in the active site
@en
Activation of phenylalanine hy ...... ire binding in the active site
@nl
type
label
Activation of phenylalanine hy ...... ire binding in the active site
@ast
Activation of phenylalanine hy ...... ire binding in the active site
@en
Activation of phenylalanine hy ...... ire binding in the active site
@nl
prefLabel
Activation of phenylalanine hy ...... ire binding in the active site
@ast
Activation of phenylalanine hy ...... ire binding in the active site
@en
Activation of phenylalanine hy ...... ire binding in the active site
@nl
P2093
P2860
P356
P1433
P1476
Activation of phenylalanine hy ...... ire binding in the active site
@en
P2093
Crystal A Khan
Cynthia S Hinck
Kenneth M Roberts
Paul F Fitzpatrick
P2860
P304
P356
10.1021/BI501183X
P407
P577
2014-12-02T00:00:00Z