A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea.
about
Arsenite-induced Cdc25C Degradation is through the KEN-box and Ubiquitin-proteasome PathwayA novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosisNormal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosisRegulating mammalian checkpoints through Cdc25 inactivation.Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinasesCell cycle regulation of the murine cdc25B promoter: essential role for nuclear factor-Y and a proximal repressor element.14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity.Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases.A general framework for modeling growth and division of mammalian cellsChk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase.Upstream and downstream of ran GTPase.Cell cycle checkpoints and their inactivation in human cancer.Changes in regulatory phosphorylation of Cdc25C Ser287 and Wee1 Ser549 during normal cell cycle progression and checkpoint arrests.Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells14-3-3 epsilon prevents G2/M transition of fertilized mouse eggs by binding with CDC25BMicroscopy-induced radiation damage, microtubules, and progression through the terminal stage of G2 (prophase) in vertebrate somatic cells.Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells.Prognostic significance of CDC25B expression in gliomasCDC25 Inhibition in Acute Myeloid Leukemia-A Study of Patient Heterogeneity and the Effects of Different Inhibitors.Nuclei and microtubule asters stimulate maturation/M phase promoting factor (MPF) activation in Xenopus eggs and egg cytoplasmic extracts.RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.CaMKK2 Suppresses Muscle Regeneration through the Inhibition of Myoblast Proliferation and Differentiation.14-3-3 proteins as signaling integration points for cell cycle control and apoptosis.Biomarkers for predicting the response of esophageal squamous cell carcinoma to neoadjuvant chemoradiation therapy.Inappropriate activation of cyclin-dependent kinases by the phosphatase Cdc25b results in premature mitotic entry and triggers a p53-dependent checkpoint.The dual specificity phosphatase Cdc25B, but not the closely related Cdc25C, is capable of inhibiting cellular proliferation in a manner dependent upon its catalytic activity.Caffeine mimics adenine and 2'-deoxyadenosine, both of which inhibit the guanine-nucleotide exchange activity of RCC1 and the kinase activity of ATR.Negative growth regulation of SK-N-MC cells by bFGF defines a growth factor-sensitive point in G2.Inhibition of cell proliferation by lithium is associated with interference in cdc2 activation.CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.MPF localization is controlled by nuclear export.Identification of a C-terminal cdc25 sequence required for promotion of germinal vesicle breakdown.Chemical activation with a combination of ionomycin and dehydroleucodine for production of parthenogenetic, ICSI and cloned bovine embryos.Cdc25B activity is regulated by 14-3-3.Nuclear localization of CDC25B1 and serine 146 integrity are required for induction of mitosis.Antisense phosphorothioate oligonucleotides specifically down-regulate cdc25B causing S-phase delay and persistent antiproliferative effects.Differential mitotic degradation of the CDC25B phosphatase variants.
P2860
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P2860
A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea.
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34
@nl
A dual-specificity phosphatase ...... lls arrested with hydroxyurea.
@ast
A dual-specificity phosphatase ...... lls arrested with hydroxyurea.
@en
type
label
A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34
@nl
A dual-specificity phosphatase ...... lls arrested with hydroxyurea.
@ast
A dual-specificity phosphatase ...... lls arrested with hydroxyurea.
@en
prefLabel
A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34
@nl
A dual-specificity phosphatase ...... lls arrested with hydroxyurea.
@ast
A dual-specificity phosphatase ...... lls arrested with hydroxyurea.
@en
P2093
P2860
P356
P1476
A dual-specificity phosphatase ...... ells arrested with hydroxyurea
@en
P2093
P2860
P304
P356
10.1083/JCB.138.5.1105
P407
P577
1997-09-01T00:00:00Z