Homology modeling of breast cancer resistance protein (ABCG2).
about
LRRML: a conformational database and an XML description of leucine-rich repeats (LRRs)Insights into Chemoresistance of Prostate CancerMarine natural products as breast cancer resistance protein inhibitorsNew tips for structure prediction by comparative modelingARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2.Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).ABCG2 transports and transfers heme to albumin through its large extracellular loopMembrane topology of the human breast cancer resistance protein (BCRP/ABCG2) determined by epitope insertion and immunofluorescence.Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter2,3-Dihydro-1-benzofuran derivatives as a series of potent selective cannabinoid receptor 2 agonists: design, synthesis, and binding mode prediction through ligand-steered modeling.Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation.In-silico analysis of caspase-3 and -7 proteases from blood-parasitic Schistosoma species (Trematoda) and their human host.Development of conformation independent computational models for the early recognition of breast cancer resistance protein substrates.Substrate-dependent breast cancer resistance protein (Bcrp1/Abcg2)-mediated interactions: consideration of multiple binding sites in in vitro assay design.Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expressionABC transporters and isothiocyanates: potential for pharmacokinetic diet-drug interactions.Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.Drug transport by breast cancer resistance protein.Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Overcoming multidrug resistance with nanomedicines.Radiopharmaceuticals for assessing ABC transporters at the blood-brain barrier.3D structural models of transmembrane proteins.Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivoBiophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins.Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance.The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone.The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport.Targeting Heat Shock Proteins 60 and 70 of Toxoplasma gondii as a Potential Drug Target: In Silico Approach.Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2.Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences.Structure-function relationships in ABCG2: insights from molecular dynamics simulations and molecular docking studies.PharmGKB summary: very important pharmacogene information for ABCG2.Quizartinib (AC220) reverses ABCG2-mediated multidrug resistance: In vitro and in vivo studies.Role of breast cancer resistance protein (BCRP) as active efflux transporter on blood-brain barrier (BBB) permeability.In silicoprediction of substrate properties for ABC-multidrug transporters
P2860
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P2860
Homology modeling of breast cancer resistance protein (ABCG2).
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Homology modeling of breast cancer resistance protein (ABCG2).
@ast
Homology modeling of breast cancer resistance protein (ABCG2).
@en
Homology modeling of breast cancer resistance protein
@nl
type
label
Homology modeling of breast cancer resistance protein (ABCG2).
@ast
Homology modeling of breast cancer resistance protein (ABCG2).
@en
Homology modeling of breast cancer resistance protein
@nl
prefLabel
Homology modeling of breast cancer resistance protein (ABCG2).
@ast
Homology modeling of breast cancer resistance protein (ABCG2).
@en
Homology modeling of breast cancer resistance protein
@nl
P1476
Homology modeling of breast cancer resistance protein (ABCG2).
@en
P2093
Eszter Hazai
Zsolt Bikádi
P356
10.1016/J.JSB.2007.12.001
P577
2007-12-15T00:00:00Z