The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.
about
The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathwayRegulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasivenessThe von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1Tumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localizationNEDD8 acts as a 'molecular switch' defining the functional selectivity of VHLJade-1, a candidate renal tumor suppressor that promotes apoptosisSynthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau proteinState of the science: an update on renal cell carcinomaThe VHL tumor suppressor: master regulator of HIFHevin is down-regulated in many cancers and is a negative regulator of cell growth and proliferationIdentification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complexConjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor functionGenetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegansSequential pathogenesis of metastatic VHL mutant clear cell renal cell carcinoma: putting it together with a translational perspectiveThe structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsVHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma.Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau proteinVHL inactivation induces HEF1 and Aurora kinase ARole of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesisVhlh gene deletion induces Hif-1-mediated cell death in thymocytespVHL function is essential for endothelial extracellular matrix deposition.Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response.The ubiquitin system, disease, and drug discovery.Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes.Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.Molecular markers of paragangliomas/pheochromocytomasThe von hippel-lindau protein suppresses androgen receptor activity.4-Pyridylanilinothiazoles that selectively target von Hippel-Lindau deficient renal cell carcinoma cells by inducing autophagic cell death.Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stabilityA CULLINary ride across the secretory pathway: more than just secretion.Screening children at risk of developing inherited endocrine neoplasia syndromes.Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.Role of chromosome 3p12-p21 tumour suppressor genes in clear cell renal cell carcinoma: analysis of VHL dependent and VHL independent pathways of tumorigenesis.Deletion of von Hippel-Lindau in glomerular podocytes results in glomerular basement membrane thickening, ectopic subepithelial deposition of collagen {alpha}1{alpha}2{alpha}1(IV), expression of neuroglobin, and proteinuria.Inherited renal cancer.VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling.Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth
P2860
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P2860
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@ast
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@en
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@nl
type
label
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@ast
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@en
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@nl
prefLabel
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@ast
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@en
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@nl
P2093
P1433
P1476
The von Hippel-Lindau tumor su ...... racellular fibronectin matrix.
@en
P2093
A O Stemmer-Rachamimov
J M Whaley
K M Lonergan
O Iliopoulos
P304
P356
10.1016/S1097-2765(00)80096-9
P577
1998-06-01T00:00:00Z