Interdomain communication revealed in the diabetes drug target mitoNEET
about
Allosteric control in a metalloprotein dramatically alters function.The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor proteinStrand swapping regulates the iron-sulfur cluster in the diabetes drug target mitoNEETGeometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State EnsembleNADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an apo-acceptor protein.Biomolecular dynamics: order-disorder transitions and energy landscapesCompetition of zinc ion for the [2Fe-2S] cluster binding site in the diabetes drug target protein mitoNEET.Redox control of human mitochondrial outer membrane protein MitoNEET [2Fe-2S] clusters by biological thiols and hydrogen peroxide.Reduction of mitochondrial protein mitoNEET [2Fe-2S] clusters by human glutathione reductase.Network visualization of conformational sampling during molecular dynamics simulation.The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease.
P2860
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P2860
Interdomain communication revealed in the diabetes drug target mitoNEET
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Interdomain communication revealed in the diabetes drug target mitoNEET
@ast
Interdomain communication revealed in the diabetes drug target mitoNEET
@en
Interdomain communication revealed in the diabetes drug target mitoNEET
@nl
type
label
Interdomain communication revealed in the diabetes drug target mitoNEET
@ast
Interdomain communication revealed in the diabetes drug target mitoNEET
@en
Interdomain communication revealed in the diabetes drug target mitoNEET
@nl
prefLabel
Interdomain communication revealed in the diabetes drug target mitoNEET
@ast
Interdomain communication revealed in the diabetes drug target mitoNEET
@en
Interdomain communication revealed in the diabetes drug target mitoNEET
@nl
P2860
P356
P1476
Interdomain communication revealed in the diabetes drug target mitoNEET
@en
P2093
Elizabeth L Baxter
Patricia A Jennings
P2860
P304
P356
10.1073/PNAS.1017604108
P407
P50
P577
2011-03-14T00:00:00Z