Assessing the potential for AAV vector genotoxicity in a murine model. - Wikidata - wikimedia - TriplyDB

Assessing the potential for AAV vector genotoxicity in a murine model.

Assessing the potential for AAV vector genotoxicity in a murine model.

http://www.wikidata.org/entity/Q34754355

about

The gene therapy journey for hemophilia: are we there yet?A short perspective on gene therapy: Clinical experience on gene therapy of gliomablastoma multiforme Adeno-associated virus-mediated microRNA delivery and therapeutics AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity Long-term correction of Sandhoff disease following intravenous delivery of rAAV9 to mouse neonates In vivo genome editing restores haemostasis in a mouse model of haemophilia Lessons Learned from Animal Models of Inherited Bleeding Disorders.Somatic Therapy of a Mouse SMA Model with a U7 snRNA Gene Correcting SMN2 Splicing Translational data from adeno-associated virus-mediated gene therapy of hemophilia B in dogs Influence of immune responses in gene/stem cell therapies for muscular dystrophies.Vector integration and tumorigenesis.rAAV-mediated tumorigenesis: still unresolved after an AAV assault Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: implications for in utero gene therapy for cystic fibrosis.High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo Empty Virions In AAV8 Vector Preparations Reduce Transduction Efficiency And May Cause Total Viral Particle Dose-Limiting Side-Effects Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.Self-complementary adeno-associated viral vectors for gene therapy of hemophilia B: progress and challenges Hitting the target without pulling the trigger AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior.Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis Integration frequency and intermolecular recombination of rAAV vectors in non-human primate skeletal muscle and liver.Induction of hepatocellular carcinoma by in vivo gene targeting.GeIST: a pipeline for mapping integrated DNA elements Telomerase gene therapy: a novel approach to combat aging Patterns of scAAV vector insertion associated with oncogenic events in a mouse model for genotoxicity Genotoxicity in Mice Following AAV Gene Delivery: A Safety Concern for Human Gene Therapy?Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction Immune responses to AAV vectors: overcoming barriers to successful gene therapy Recombinant AAV Integration Is Not Associated With Hepatic Genotoxicity in Nonhuman Primates and Patients Low-dose Gene Therapy Reduces the Frequency of Enzyme Replacement Therapy in a Mouse Model of Lysosomal Storage Disease.Gene therapy for haemophilia: a long and winding road.Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon.Safety profile of recombinant adeno-associated viral vectors: focus on alipogene tiparvovec (Glybera®).Gene delivery in tissue engineering and regenerative medicine.Developments in Viral Vector-Based Vaccines.Progress toward improved therapies for inborn errors of metabolism.Adeno-Associated Virus Gene Therapy for Liver Disease.Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity.Current and future prospects for hemophilia gene therapy.Recombinant Adeno-Associated Viral Integration and Genotoxicity: Insights from Animal Models.

P2860

Q26823818-3A88A2B2-34CB-41E8-86EA-95AE8C3ED008 Q26849375-DF99F5C3-DB92-4F75-9AF6-EF5918D0341E Q27005597-7A15DAC0-118F-4842-8BE3-7CEE339894C7 Q27318266-82EB6A4E-1429-40C1-8756-D8DB3BB98D9F Q27318381-D98B8787-22CB-4BB1-AFD1-D7C5620A30A6 Q28241725-55EF7C29-9347-49E1-8DC4-73CC4C9F7739 Q30409863-7EBBE65B-4799-443C-9461-F239EEDCDD73 Q30828907-EC8D8852-761F-4A82-A91D-D861125923FB Q30891500-90983D90-4203-4C8D-A081-778D3012FEBA Q33736192-6E936AC1-86E2-4897-8782-182144229BE6 Q33782783-7B09F321-D65C-4C34-82D7-8EC5F3B945AD Q34310293-D2C99DEE-B473-49B0-8049-4E276E06287D Q34399258-9181966C-4BC8-4211-93EC-03D3744CA065 Q34629995-4E9D4183-0442-4EE2-9C59-5FAEBEBEC1F4 Q34632510-213028C3-9435-47BD-B967-BDB4D8E6B716 Q35056714-96CC3D0E-64C7-4FCD-9F3A-7F2D423FDA22 Q35431994-A2FDE9EC-9A6D-4D1E-8480-289F752B9E7E Q35591457-525925D1-1B10-43F8-A967-3882771A56FB Q35988700-762B6E75-AA2F-4C16-B957-5476885C1FC1 Q36013060-434AE3DD-77BA-4EBB-898E-F1209BE9A86F Q36014088-5DDA8504-BA9B-4903-B297-F78D61B75BCF Q36094151-55BDC4CD-4E2E-4290-B637-CBE2D76BC909 Q36117412-B3B63506-EEE8-4EA8-BC5C-39584A7EC4EA Q36386433-861659CF-DAF4-4007-8528-4A36BA836007 Q36401085-F4177C9D-6081-44FF-8AEE-F859EA029FC3 Q36756903-99CB43F1-9814-436E-8B07-ED8BF330FC59 Q36848708-4E016F99-6BC1-4F1C-80C7-C8D5F19987C7 Q36983740-93774CAF-19FF-48E1-976A-B43CF73BB423 Q37043497-9B3D0925-DE63-498F-BFA1-131ACBBC6395 Q37507816-353188AA-052C-422A-AAFF-0A13AA7FF712 Q37903924-C05C7CCA-3209-47D8-86EA-F39074B6E2F2 Q37937458-826117E6-6B74-4204-84AC-29F7FD52CD9A Q38168940-74AE790C-6FA6-4D14-A72E-861B9B2190EA Q38306886-AF9A28C1-8A6F-4205-86BC-F6C96ACDB940 Q38582090-45AAEA74-640A-4DE1-80EC-92CE936A1CD1 Q38601073-531A9BD3-4CE6-432B-8F24-4410253111E3 Q38789554-E8293E20-0B50-4D20-9147-50A664743A47 Q38809600-A72960AD-6B5F-49E3-9E2F-E767ED16F805 Q38827606-6ADEC387-A028-427E-B21B-94523728D8FD Q38907797-B2BDBC7A-BCDC-46D2-A910-364D9D91F001

P2860

Assessing the potential for AAV vector genotoxicity in a murine model.

http://www.wikidata.org/entity/Q34754355

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Assessing the potential for AAV vector genotoxicity in a murine model.

@ast

Assessing the potential for AAV vector genotoxicity in a murine model.

@en

Assessing the potential for AAV vector genotoxicity in a murine model.

@nl

type

label

Assessing the potential for AAV vector genotoxicity in a murine model.

@ast

Assessing the potential for AAV vector genotoxicity in a murine model.

@en

Assessing the potential for AAV vector genotoxicity in a murine model.

@nl

prefLabel

Assessing the potential for AAV vector genotoxicity in a murine model.

@ast

Assessing the potential for AAV vector genotoxicity in a murine model.

@en

Assessing the potential for AAV vector genotoxicity in a murine model.

@nl

P1433

Q34754355-8DAFF56D-F4F2-4B9D-BD03-E6CD166F0370

P1476

Q34754355-18F939A7-0006-4C46-8FC9-A538FA15EB88

P2093

Q34754355-2660CB90-4F1E-4BC1-84C7-AD886D16665A

Q34754355-5B80B08B-FDF5-4CEC-9757-05F8B4D18C11

Q34754355-5C4154A8-CA27-4CB6-9B0B-316F71B8D907

Q34754355-869B71F9-D76C-4E41-9BFD-372D1D6DB454

Q34754355-8E663C01-4F51-410D-AC72-8664BF9E7A56

Q34754355-BA68871F-574F-49BE-92A1-DB91AAD48781

Q34754355-BA71374F-6173-41AF-9481-553B73C27B70

Q34754355-BC3F6357-2BF0-442B-861D-1C723808E2E0

Q34754355-DDC3BD66-186B-4510-A805-14FD2C832D44

Q34754355-EE8A368C-FFD4-403A-BB26-BDE744CF611B

P2860

Q34754355-037C046C-9914-46F4-9586-4AA0FE3166B7

Q34754355-08B5B641-3F32-44CD-A2E1-84738DE51B2E

Q34754355-1098DBAF-B30C-49D2-93EB-EAB4E521D333

Q34754355-10F4D411-FEF6-4D49-92D1-EE3164FC2974

Q34754355-1551E826-3E2C-4FD4-956B-C84CA003A5AA

Q34754355-187DC37A-25EA-4685-9E10-95AD17C8C35E

Q34754355-1FAE3389-575C-49B4-83F7-5D76A0013B33

Q34754355-1FC75D31-7718-4F01-98D2-FEEEC074253F

Q34754355-2277D4C8-6545-4104-8FEA-43F2835C7357

Q34754355-2718FE42-3463-4428-84DE-236F0385E948

P304

Q34754355-446C970A-DBFB-48B8-A59C-C59EC578E055

P31

Q34754355-48445A12-8EE3-4BE1-8F91-CE3F54B6CD9A

P356

Q34754355-54112E4C-7A94-4E6E-91C7-46A14185149A

P407

Q34754355-8F7BC134-8F85-4310-89EA-F99CDAF8177E

P433

Q34754355-FC1C9789-530C-4ABD-9D59-2EA3D0F9B17E

P478

Q34754355-1C4AFEC1-2B6B-4970-B3B5-18410D1A1BFC

P50

Q34754355-3A9F3D4A-DD35-4078-8149-C6E65B2F1FD1

Q34754355-3DBF92A7-E3DF-4898-BCCA-5DD8ACF9C00A

P577

Q34754355-DAA03F99-C51A-48D5-8011-FD2EA2A4E6F0

P5875

Q34754355-30B00D90-BBFF-4579-B491-C75CA3AC1E76

P698

Q34754355-22FE8CC9-F0DE-4A9A-9369-E1A0DFD15612

P932

Q34754355-BA347F5F-5BCE-45C4-B0A4-1F0F119933C5

P356

BLOOD-2010-08-302729

P1433

P1476

Assessing the potential for AAV vector genotoxicity in a murine model.

@en

P2093

Alexander Schlachterman

http://www.w3.org/2001/XMLSchema#string

Federico Mingozzi

http://www.w3.org/2001/XMLSchema#string

Giulio Bussadori

http://www.w3.org/2001/XMLSchema#string

Hojun Li

http://www.w3.org/2001/XMLSchema#string

J Fraser Wright

http://www.w3.org/2001/XMLSchema#string

Nirav Malani

http://www.w3.org/2001/XMLSchema#string

Rachel Shah

http://www.w3.org/2001/XMLSchema#string

Shari R Hamilton

http://www.w3.org/2001/XMLSchema#string

Shyrie E Edmonson

http://www.w3.org/2001/XMLSchema#string

Valder R Arruda

http://www.w3.org/2001/XMLSchema#string

P2860

Genome sequencing in microfabricated high-density picolitre reactors

Safety and efficacy of gene transfer for Leber's congenital amaurosis

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

Selection of target sites for mobile DNA integration in the human genome

HIV-1 integration in the human genome favors active genes and local hotspots

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting.

Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver.

P304

3311-3319

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1182/BLOOD-2010-08-302729

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

117

http://www.w3.org/2001/XMLSchema#string

P50

Frederic D. Bushman

Katherine A High

P577

2010-11-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49635212

http://www.w3.org/2001/XMLSchema#string

P698

21106988

http://www.w3.org/2001/XMLSchema#string

P932

3069673

http://www.w3.org/2001/XMLSchema#string