Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression - Wikidata - wikimedia - TriplyDB

Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

http://www.wikidata.org/entity/Q34755408

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A decade of exploring the cancer epigenome - biological and translational implications Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies How animal models of leukaemias have already benefited patients Genome sequencing and cancer Emerging patterns of somatic mutations in cancer Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A The origin and evolution of mutations in acute myeloid leukemia Global regulatory architecture of human, mouse and rat tissue transcriptomes.Molecular Profiling: A Case of ZBTB16-RARA Acute Promyelocytic Leukemia.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer.Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia.Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect.Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studies The genetics of splicing in neuroblastoma.Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells.X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia.JAK Kinases in Health and Disease: An Update Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles.Pathways of retinoid synthesis in mouse macrophages and bone marrow cells Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia.PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL.Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis Notch signaling in acute promyelocytic leukemia Induced pluripotent stem cell generation-associated point mutations arise during the initial stages of the conversion of these cells.Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.Genomics of acute myeloid leukemia: the next generation.Cancer of mice and men: old twists and new tails.Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers.Genome-scale technology driven advances to research into normal and malignant haematopoiesis.Genetic mutations in epigenetic modifiers as therapeutic targets in acute myeloid leukemia.A case of me: clinical cancer sequencing and the future of precision medicine.

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Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

http://www.wikidata.org/entity/Q34755408

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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Sequencing a mouse acute promy ...... levant for disease progression

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Sequencing a mouse acute promy ...... levant for disease progression

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Sequencing a mouse acute promy ...... levant for disease progression

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Sequencing a mouse acute promy ...... levant for disease progression

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Sequencing a mouse acute promy ...... levant for disease progression

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Sequencing a mouse acute promy ...... levant for disease progression

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Journal of Clinical Investigation

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Sequencing a mouse acute promy ...... levant for disease progression

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Adam F Dukes

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Cheng Li

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Daniel C Koboldt

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David E Larson

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Elaine R Mardis

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Heather Schmidt

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Jacqueline E Payton

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Jeffery M Klco

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Joelle Kalicki

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John S Welch

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P2860

Significance analysis of microarrays applied to the ionizing radiation response

Recurring mutations found by sequencing an acute myeloid leukemia genome

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

Mapping short DNA sequencing reads and calling variants using mapping quality scores

High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples

Fast and accurate short read alignment with Burrows-Wheeler transform

A high-resolution map of segmental DNA copy number variation in the mouse genome

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.

The Sequence Alignment/Map format and SAMtools

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10.1172/JCI45284

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Timothy A. Graubert

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2011-03-23T00:00:00Z

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