A new class of anthelmintics effective against drug-resistant nematodes. - Wikidata - wikimedia - TriplyDB

A new class of anthelmintics effective against drug-resistant nematodes.

A new class of anthelmintics effective against drug-resistant nematodes.

http://www.wikidata.org/entity/Q34761361

about

The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets Genome and transcriptome of the porcine whipworm Trichuris suis Ascaris suum draft genome Developing novel anthelmintics from plant cysteine proteinases.Screening of the 'Pathogen Box' identifies an approved pesticide with major anthelmintic activity against the barber's pole worm Nematode phospholipid metabolism: an example of closing the genome-structure-function circle Potential drug development candidates for human soil-transmitted helminthiases The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants Principles of agonist recognition in Cys-loop receptors Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel Phylogenomics of ligand-gated ion channels predicts monepantel effect The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections Introgression of ivermectin resistance genes into a susceptible Haemonchus contortus strain by multiple backcrossing A molecular diagnostic tool to replace larval culture in conventional faecal egg count reduction testing in sheep Bacillus thuringiensis-derived Cry5B has potent anthelmintic activity against Ascaris suum Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro Systematic analysis of insertions and deletions specific to nematode proteins and their proposed functional and evolutionary relevance.The novel nematicide wact-86 interacts with aldicarb to kill nematodes.Suppression of aquaporin, a mediator of water channel control in the carcinogenic liver fluke, Opisthorchis viverrini.The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility In silico approach to screen compounds active against parasitic nematodes of major socio-economic importance.Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans.Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit.Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.The Conqueror Worm: recent advances with cholinergic anthelmintics and techniques excite research for better therapeutic drugs.Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.Anthelmintic resistance: markers for resistance, or susceptibility?Ion channels and drug transporters as targets for anthelmintics.Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand acr-23 Encodes a monepantel-sensitive channel in Caenorhabditis elegans.First report of monepantel Haemonchus contortus resistance on sheep farms in Uruguay.

P2860

Q21183984-4AD1ACB6-41B1-42AA-BF8E-ED8F707A5BF4 Q22065964-269BABFB-308A-47E4-A5D0-7C522A6F2FF6 Q22122068-A0987A58-569E-485A-9D33-8E7F2373E9C4 Q22122174-1FCBE397-41CD-4106-A8D9-5A6B96925100 Q24658119-627845E0-8439-49ED-83AD-72165A0541B4 Q26741549-FD0B4652-AB3B-4AB4-BD2B-474C84F4D86C Q26853143-A27D7EA3-47E8-4AB2-B271-7206A4724F20 Q27306274-2C0DC60D-CE58-402C-BBAC-280B8EB57722 Q27306806-4FB3B598-DACB-49FC-830F-CFB72D46F1D5 Q27312012-F053A949-1BD1-4F26-95AD-DE0177B1AE09 Q28239408-C27FE5A2-4097-428D-8A03-87DE38E44436 Q28383181-D94125A0-CF4D-4DB2-8841-2804FB3791D2 Q28475244-7B08B358-4EBE-41B8-B5C2-8A67C1E7B7B8 Q28475454-F8958BCD-42FA-4638-9283-EDB694D54397 Q28475744-0AA9ED80-590F-4436-9508-F9C97786297B Q28476559-56499AD5-6D58-47E4-9648-3F36AF7DAFE3 Q28478581-906A2CF6-5DEF-46C8-AF0D-51C9E26A874E Q28480879-DA5A0344-F5F6-458D-BB73-4378B178D98E Q28483885-09CF57CB-CCD5-4405-ADA0-B7A6B7038694 Q28534011-3343A219-B63F-4A76-B448-1C5EE940D023 Q28542769-12FB4E54-7214-4732-AA1F-CBD6B5D2A1C0 Q28552737-9E1CA6F9-876D-4EA8-86CA-370B9C141CA2 Q28828547-E0F44DD3-105B-4425-BAB7-A0EE906C208C Q33403657-3DAD655C-43DA-40C3-8923-5D781D98EA66 Q33570926-EE1EB558-5252-4145-9264-96B0D2282644 Q33662665-84FA9204-62BA-468A-9842-DB07A43C10B6 Q33741666-895A8F84-C7F8-4381-A0FF-7A1B73C2DFB6 Q33778375-7D2E0985-F8DA-4FA7-994D-C498B08D5813 Q34176063-CF493E12-D13D-465A-98DD-966BEE1D02AF Q34248454-171AAAFA-EEA3-4E87-AD8F-62584BEE46B2 Q34295982-54316E6C-5AD3-4D20-8DE0-A34988E9C52A Q34299221-A2C92FF4-4A61-4859-A6A3-6682D93716E8 Q34587731-C6FC79CF-02B3-49EB-A9F0-0A978F3057EE Q34705912-AD5388C3-BE8E-4C09-B176-0D1AEBCFB320 Q34721432-AAD136C7-2CF5-4221-8ADB-01D8D058486F Q34782668-4B2C15D7-BCEE-4258-ADFF-32BB5E5C30EF Q34804747-AB4128FF-6630-462C-9C22-DFA0547E8989 Q34863653-B3DA85EB-E3EE-4684-8F85-ACA6332FE695 Q34945410-7FCC4916-6506-4B38-A1C9-C0AA9BD161B8 Q35008692-329CF280-9077-48EF-A506-80028F042E16

P2860

A new class of anthelmintics effective against drug-resistant nematodes.

http://www.wikidata.org/entity/Q34761361

description

2008 nî lūn-bûn

@nan

2008 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի մարտին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

A new class of anthelmintics effective against drug-resistant nematodes.

@ast

A new class of anthelmintics effective against drug-resistant nematodes.

@en

A new class of anthelmintics effective against drug-resistant nematodes.

@nl

type

label

A new class of anthelmintics effective against drug-resistant nematodes.

@ast

A new class of anthelmintics effective against drug-resistant nematodes.

@en

A new class of anthelmintics effective against drug-resistant nematodes.

@nl

prefLabel

A new class of anthelmintics effective against drug-resistant nematodes.

@ast

A new class of anthelmintics effective against drug-resistant nematodes.

@en

A new class of anthelmintics effective against drug-resistant nematodes.

@nl

P1433

Q34761361-6ABD3A21-8342-4AE9-8F21-F934B9BB811A

P1476

Q34761361-A931EC25-4E92-4462-8C8F-3CC0BB22AC2D

P2093

Q34761361-0207B2F6-3C75-4C20-85A3-68CE59434761

Q34761361-04DAE7BB-2734-4D5F-B192-CD898CC42FFC

Q34761361-12725312-3E67-4F7E-95F2-D5F45CAB5FFD

Q34761361-1424C380-6B22-4738-A382-929B09A30C76

Q34761361-36D79B8D-550E-4BA0-B977-792F7EE002AB

Q34761361-3D67EDF8-2E6F-4535-BC1A-414E7AF2FBA6

Q34761361-3F790BE6-2AB0-43CC-9A49-695F7E397EFA

Q34761361-42A7FB35-46CE-4806-9CE0-DA1071A23420

Q34761361-6240E0F8-4962-41A3-8A1C-9C97E7A16BAD

Q34761361-70A0564D-80AA-4904-A986-FB10F8B8334C

P2888

Q34761361-8EA59166-2CA3-4F6E-9578-219815BC6DFF

P304

Q34761361-AC940A1A-E3EE-4EA8-B9C1-30CE38B776D5

P31

Q34761361-210EA8B1-8993-49E3-AC6F-99A676CA7F0E

P356

Q34761361-3BE7306D-778D-4F93-8EAE-8414EC469F14

P407

Q34761361-B607E51B-6CEB-4BF2-B454-9F4752BBE66F

P433

Q34761361-923BE90A-12E5-49E2-9868-57CF3B941E1C

P478

Q34761361-219AFC9F-40FB-468A-BD69-8C15193065A8

P50

Q34761361-2D80836F-7559-4CFA-83EA-BE27DC01BA11

P577

Q34761361-C2EF5749-D052-4322-AB3B-5570168D9BD4

P5875

Q34761361-BFE20B64-B930-4B98-9D46-4A94835FF87E

P6179

Q34761361-087A5282-6412-486C-93A7-8FAC15211B6E

P698

Q34761361-79EC031B-451D-4DC0-9E73-133F25942314

P356

P1433

P1476

A new class of anthelmintics effective against drug-resistant nematodes.

@en

P2093

Andre Wenger

http://www.w3.org/2001/XMLSchema#string

Ann Sluder

http://www.w3.org/2001/XMLSchema#string

Bethany Westlund

http://www.w3.org/2001/XMLSchema#string

Clarisse Komoin-Oka

http://www.w3.org/2001/XMLSchema#string

François Pautrat

http://www.w3.org/2001/XMLSchema#string

Jacques Bouvier

http://www.w3.org/2001/XMLSchema#string

Lucien Rufener

http://www.w3.org/2001/XMLSchema#string

Martin Jung

http://www.w3.org/2001/XMLSchema#string

Noelle Gauvry

http://www.w3.org/2001/XMLSchema#string

Olivier Froelich

http://www.w3.org/2001/XMLSchema#string

P2888

P304

176-180

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NATURE06722

http://www.w3.org/2001/XMLSchema#string

P407

P433

7184

http://www.w3.org/2001/XMLSchema#string

P478

452

http://www.w3.org/2001/XMLSchema#string

P50

P577

2008-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5514116

http://www.w3.org/2001/XMLSchema#string

P6179

1004605435

http://www.w3.org/2001/XMLSchema#string

P698

18337814

http://www.w3.org/2001/XMLSchema#string