A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.
about
Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice.Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterningActivation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replicationCooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expressionEnhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axisARTS and Siah collaborate in a pathway for XIAP degradationOverexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs.Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation.Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter.Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation functionCRE recombinase-inducible RNA interference mediated by lentiviral vectorsInhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin ANF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survivalBRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cellsOptimization of feline immunodeficiency virus vectors for RNA interferenceTowards in vivo application of RNA interference - new toys, old problemsSingle copy shRNA configuration for ubiquitous gene knockdown in miceShort-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectorsAn RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAiEfficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivoInsights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imagingCurrent advances in Phi29 pRNA biology and its application in drug deliveryp53 protects against genome instability following centriole duplication failureEps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)Insertional mutagenesis in mice: new perspectives and toolsCombinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processingSUMO1-dependent modulation of SERCA2a in heart failure.Efficacy and Mechanism of Action of Low Dose Emetine against Human CytomegalovirusPolycystic kidney disease prevented by transgenic RNA interferenceAntiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cellsGeneration of tissue-specific transgenic birds with lentiviral vectors.Systemic delivery of shRNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart, but not liver.Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxietyDevelopment of functional human embryonic stem cell-derived neurons in mouse brain.Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories.The Use of Lentiviral Vectors and Cre/loxP to Investigate the Function of Genes in Complex BehaviorsAmygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice.Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis
P2860
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P2860
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
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2003年學術文章
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name
A general method for gene knoc ...... ressing small interfering RNA.
@ast
A general method for gene knoc ...... ressing small interfering RNA.
@en
A general method for gene knoc ...... ressing small interfering RNA.
@nl
type
label
A general method for gene knoc ...... ressing small interfering RNA.
@ast
A general method for gene knoc ...... ressing small interfering RNA.
@en
A general method for gene knoc ...... ressing small interfering RNA.
@nl
prefLabel
A general method for gene knoc ...... ressing small interfering RNA.
@ast
A general method for gene knoc ...... ressing small interfering RNA.
@en
A general method for gene knoc ...... ressing small interfering RNA.
@nl
P2860
P356
P1476
A general method for gene knoc ...... pressing small interfering RNA
@en
P2093
Inder M Verma
Oded Singer
P2860
P304
P356
10.1073/PNAS.0437912100
P407
P577
2003-01-27T00:00:00Z