M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms.
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Quantitative modeling of GRK-mediated beta2AR regulationStrike a pose: Gαq complexes at the membraneSite-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling.cAMP-dependent and cholinergic regulation of the electrogenic intestinal/pancreatic Na+/HCO3- cotransporter pNBC1 in human embryonic kidney (HEK293) cells.Isoproterenol and cAMP block ERK phosphorylation and enhance [Ca2+]i increases and oxygen consumption by muscarinic receptor stimulation in rat parotid and submandibular acinar cells.Sodium and potassium regulate endothelial phospholipase C-γ and Bmx.RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivoThe M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent mannerInternalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activationBiased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanineIncreased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophreniaAn N-terminal polybasic motif of Gαq is required for signaling and influences membrane nanodomain distribution.M3-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1.Structural determinants in the second intracellular loop of the human cannabinoid CB1 receptor mediate selective coupling to G(s) and G(i)Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.M1 muscarinic receptor activation mediates cell death in M1-HEK293 cellsRegulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.A single mutation in arrestin-2 prevents ERK1/2 activation by reducing c-Raf1 binding.Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorderEndogenously expressed muscarinic receptors in HEK293 cells augment up-regulation of stably expressed α4β2 nicotinic receptors.Arrestin development: emerging roles for beta-arrestins in developmental signaling pathwaysRegulation of α(2B)-adrenergic receptor-mediated extracellular signal-regulated kinase 1/2 (ERK1/2) activation by ADP-ribosylation factor 1.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsTricyclic Antidepressant Amitriptyline-induced Glial Cell Line-derived Neurotrophic Factor Production Involves Pertussis Toxin-sensitive Gαi/o Activation in Astroglial Cells.G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro.Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways.The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions.CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo.Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms.The mechanism and function of mitogen-activated protein kinase activation by ARF1.Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptorsEnhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor DesensitizationThe β-Arrestins: Multifunctional Regulators of G Protein-coupled ReceptorsRich tapestry of G protein-coupled receptor signaling and regulatory mechanisms.Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling.Muscarinic type 3 receptor autoantibodies are associated with anti-SSA/Ro autoantibodies in Sjögren's syndrome
P2860
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P2860
M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@ast
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@en
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@nl
type
label
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@ast
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@en
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@nl
prefLabel
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@ast
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@en
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@nl
P2093
P356
P1476
M3 muscarinic acetylcholine re ...... ulated by distinct mechanisms.
@en
P2093
Jeffrey L Benovic
Jiansong Luo
John M Busillo
P304
P356
10.1124/MOL.107.044750
P577
2008-04-03T00:00:00Z