Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.
about
Pathogenic mechanisms in centronuclear myopathiesMaking muscle elastic: the structural basis of myomesin stretchingSuperhelical architecture of the myosin filament-linking protein myomesin with unusual elastic propertiesα-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titinInteractions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnoverMechanoenzymatics of titin kinase.Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titinFormin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenanceObscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnoverExome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growthTropomodulin capping of actin filaments in striated muscle development and physiologyAlp/Enigma family proteins cooperate in Z-disc formation and myofibril assemblyLarge isoforms of UNC-89 (obscurin) are required for muscle cell architecture and optimal calcium release in Caenorhabditis elegansStructural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complexThe SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle.A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle.Biophysical characterization of naturally occurring titin M10 mutationsDeregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurinTargeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain developmentLoss of giant obscurins promotes breast epithelial cell survival through apoptotic resistanceObscure functions: the location-function relationship of obscurins.Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies.Permanent cardiac sarcomere changes in a rabbit model of intrauterine growth restrictionDevelopmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.Muscle giants: molecular scaffolds in sarcomerogenesis.Obscurins: Goliaths and Davids take over non-muscle tissues.Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers.Gene expression profiling in tibial muscular dystrophy reveals unfolded protein response and altered autophagy.Fast-folding alpha-helices as reversible strain absorbers in the muscle protein myomesinOBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency.Three-dimensional structure of the M-region (bare zone) of vertebrate striated muscle myosin filaments by single-particle analysis.Myofibrillogenesis regulator 1 induces hypertrophy by promoting sarcomere organization in neonatal rat cardiomyocytes.Hydrophobic residues in small ankyrin 1 participate in binding to obscurin.Contribution of the OBSCN nonsynonymous variants to aspirin exacerbated respiratory disease susceptibility in Korean population.Altered contractility of skeletal muscle in mice deficient in titin's M-band region.The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila.Functional classification of skeletal muscle networks. I. Normal physiology.Titin and obscurin: giants holding hands and discovery of a new Ig domain subsetObscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity.
P2860
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P2860
Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Interactions with titin and my ...... ons for hereditary myopathies.
@ast
Interactions with titin and my ...... ons for hereditary myopathies.
@en
Interactions with titin and my ...... ons for hereditary myopathies.
@nl
type
label
Interactions with titin and my ...... ons for hereditary myopathies.
@ast
Interactions with titin and my ...... ons for hereditary myopathies.
@en
Interactions with titin and my ...... ons for hereditary myopathies.
@nl
prefLabel
Interactions with titin and my ...... ons for hereditary myopathies.
@ast
Interactions with titin and my ...... ons for hereditary myopathies.
@en
Interactions with titin and my ...... ons for hereditary myopathies.
@nl
P2093
P356
P1476
Interactions with titin and my ...... ions for hereditary myopathies
@en
P2093
Ana Ferreiro
Anna Vihola
Atsushi Fukuzawa
Bjarne Udd
Virginie Carmignac
P304
P356
10.1242/JCS.028019
P407
P577
2008-05-13T00:00:00Z