Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies. - Wikidata - wikimedia - TriplyDB

Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.

Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.

http://www.wikidata.org/entity/Q34778428

about

Pathogenic mechanisms in centronuclear myopathies Making muscle elastic: the structural basis of myomesin stretching Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties α-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover Mechanoenzymatics of titin kinase.Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth Tropomodulin capping of actin filaments in striated muscle development and physiology Alp/Enigma family proteins cooperate in Z-disc formation and myofibril assembly Large isoforms of UNC-89 (obscurin) are required for muscle cell architecture and optimal calcium release in Caenorhabditis elegans Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle.A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle.Biophysical characterization of naturally occurring titin M10 mutations Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance Obscure functions: the location-function relationship of obscurins.Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies.Permanent cardiac sarcomere changes in a rabbit model of intrauterine growth restriction Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.Muscle giants: molecular scaffolds in sarcomerogenesis.Obscurins: Goliaths and Davids take over non-muscle tissues.Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers.Gene expression profiling in tibial muscular dystrophy reveals unfolded protein response and altered autophagy.Fast-folding alpha-helices as reversible strain absorbers in the muscle protein myomesin OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency.Three-dimensional structure of the M-region (bare zone) of vertebrate striated muscle myosin filaments by single-particle analysis.Myofibrillogenesis regulator 1 induces hypertrophy by promoting sarcomere organization in neonatal rat cardiomyocytes.Hydrophobic residues in small ankyrin 1 participate in binding to obscurin.Contribution of the OBSCN nonsynonymous variants to aspirin exacerbated respiratory disease susceptibility in Korean population.Altered contractility of skeletal muscle in mice deficient in titin's M-band region.The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila.Functional classification of skeletal muscle networks. I. Normal physiology.Titin and obscurin: giants holding hands and discovery of a new Ig domain subset Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity.

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Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.

http://www.wikidata.org/entity/Q34778428

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Interactions with titin and my ...... ons for hereditary myopathies.

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Ana Ferreiro

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Anna Vihola

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Atsushi Fukuzawa

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Mark Holt

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