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Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesinObscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnoverCyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signalingRigid conformation of an immunoglobulin domain tandem repeat in the A-band of the elastic muscle protein titinSubcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminusPalindromic assembly of the giant muscle protein titin in the sarcomeric Z-diskDimerisation of myomesin: implications for the structure of the sarcomeric M-bandMyomesin 3, a novel structural component of the M-band in striated muscleExploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.Cypher/ZASP is a novel A-kinase anchoring protein.The kinase domain of titin controls muscle gene expression and protein turnover.Probing muscle ankyrin-repeat protein (MARP) structure and functionInteractions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.M-band: a safeguard for sarcomere stability?Cypher and Enigma homolog protein are essential for cardiac development and embryonic survivalA novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.From A to Z and back? Multicompartment proteins in the sarcomere.MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy.Isolation and culture of neonatal mouse cardiomyocytes.Reply: Hereditary myopathy with early respiratory failure is caused by mutations in the titin FN3 119 domain.Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy.Cathepsins in heart disease-chewing on the heartache?Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice.Cullin E3 Ligase Activity Is Required for Myoblast Differentiation.Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletionThe sarcomeric M-band during development and in diseaseMurine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolismPKC and PKN in heart diseaseCullin-3 dependent deregulation of ACTN1 represents a new pathogenic mechanism in nemaline myopathy.miR-486 is modulated by stretch and increases ventricular growthComparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serumThe M-band: The underestimated part of the sarcomere
P50
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P50
description
onderzoeker
@nl
researcher, ORCID id # 0000-0001-9361-6602
@en
name
Stephan Lange
@ast
Stephan Lange
@en
Stephan Lange
@es
Stephan Lange
@nl
type
label
Stephan Lange
@ast
Stephan Lange
@en
Stephan Lange
@es
Stephan Lange
@nl
prefLabel
Stephan Lange
@ast
Stephan Lange
@en
Stephan Lange
@es
Stephan Lange
@nl
P106
P31
P496
0000-0001-9361-6602