The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes. - Wikidata - wikimedia - TriplyDB

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

http://www.wikidata.org/entity/Q34790844

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Novel LMX1B mutation in familial nail-patella syndrome with variable expression of open angle glaucoma Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability In vivo expression of putative LMX1B targets in nail-patella syndrome kidneys Podocytes Cell biology and pathology of podocytes The structural and functional organization of the podocyte filtration slits is regulated by Tjp1/ZO-1 Generation of Pet1210-Cre transgenic mouse line reveals non-serotonergic expression domains of Pet1 both in CNS and periphery Development of the Mammalian Kidney Genotype-phenotype studies in nail-patella syndrome show that LMX1B mutation location is involved in the risk of developing nephropathy Large-scale identification of genes implicated in kidney glomerulus development and function.LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys.The glomerulus--a view from the outside--the podocyte.TGF-β-activated kinase 1 is crucial in podocyte differentiation and glomerular capillary formation.NPHS2 (Podocin) mutations in nephrotic syndrome. Clinical spectrum and fine mechanisms.A microdeletion of chromosome 9q33.3 encompasses the entire LMX1B gene in a Chinese family with nail patella syndrome.Advances in the biology and genetics of the podocytopathies: implications for diagnosis and therapy Nail patella syndrome: a review of the phenotype aided by developmental biology Glomerular proteinuria: a complex interplay between unique players.A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected].Nail-patella syndrome and its association with glaucoma: a review of eight families Transcriptional regulation of podocyte disease Early glomerular filtration defect and severe renal disease in podocin-deficient mice Human syndromes with congenital patellar anomalies and the underlying gene defects.LMX1B mutations cause hereditary FSGS without extrarenal involvement Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression.Kidney disease in nail-patella syndrome Manifold functions of the Nail-Patella Syndrome gene Lmx1b in vertebrate development.Dysregulation of WTI (-KTS) is Associated with the Kidney-Specific Effects of the LMX1B R246Q Mutation.Basement membranes in development and disease.The signaling pathways of LMX1B and its role in glomerulosclerosis.Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus.Understanding podocytopathy and its relevance to clinical nephrology.LIM homeobox transcription factor 1B is associated with pro-fibrotic components and apoptosis in hypoxia/reoxygenation renal tubular epithelial cells.Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation Excess podocyte semaphorin-3A leads to glomerular disease involving plexinA1-nephrin interaction.Lmx1b and FoxC combinatorially regulate podocin expression in podocytes.Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development.How are podocytes affected in nail-patella syndrome?LIM homeobox transcription factor 1B expression affects renal interstitial fibrosis and apoptosis in unilateral ureteral obstructed rats.Nail patella syndrome revisited: 50 years after linkage.

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P2860

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

http://www.wikidata.org/entity/Q34790844

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

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The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

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The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

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type

label

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

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The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

@en

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

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prefLabel

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

@ast

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

@en

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

@nl

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Journal of Clinical Investigation

P1476

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.

@en

P2093

Claudia Rohr

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Hiltraud Hosser

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Jürgen Prestel

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Randy L Johnson

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Wilhelm Kriz

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P2860

Mutation analysis of LMX1B gene in nail-patella syndrome patients

LMX1B transactivation and expression in nail-patella syndrome

Podocin localizes in the kidney to the slit diaphragm area

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome

Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin

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1073-1082

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scholarly article

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10.1172/JCI0213961

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8

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109

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Corinne Antignac

Laurence Heidet

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2002-04-01T00:00:00Z

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11956245

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P932

150943

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