The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. - Wikidata - wikimedia - TriplyDB

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

http://www.wikidata.org/entity/Q34801853

about

Akt and mTOR in B Cell Activation and Differentiation Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1 Regulation of TOR by small GTPases Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells Balancing Inflammation: The Link between Th17 and Regulatory T Cells The Mucosal Immune System and Its Regulation by Autophagy Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation mTOR Regulation of Lymphoid Cells in Immunity to Pathogens Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis Signaling in T cells - is anything the m(a)TOR with the picture(s)?The Macrophage Switch in Obesity Development Inducing and Administering Tregs to Treat Human Disease Metabolic regulation of T cell differentiation and function T cell metabolism drives immunity The role and regulation of mTOR in T-lymphocyte function Integrating canonical and metabolic signalling programmes in the regulation of T cell responses Metabolic regulation of regulatory T cell development and function FOXO transcription factors throughout T cell biology Ubiquitin-dependent regulation of Foxp3 and Treg function STAT6-dependent and -independent mechanisms in Th2 polarization Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging The differential expression of IL-4 and IL-13 and its impact on type-2 immunity Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice PI3K and cancer: lessons, challenges and opportunities The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells.SGK1: The Dark Side of PI3K Signaling.Analysis of sirtuin 1 expression reveals a molecular explanation of IL-2-mediated reversal of T-cell tolerance miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation Highlights of the advances in basic immunology in 2011.Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation.ISA-2011B, a Phosphatidylinositol 4-Phosphate 5-Kinase α Inhibitor, Impairs CD28-Dependent Costimulatory and Pro-inflammatory Signals in Human T Lymphocytes.Oxidative stress in the pathology and treatment of systemic lupus erythematosus HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.A tightly regulated IL-22 response maintains immune functions and homeostasis in systemic viral infection.Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.

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The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

http://www.wikidata.org/entity/Q34801853

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The kinase mTOR regulates the ...... ignaling by mTORC1 and mTORC2.

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The kinase mTOR regulates the ...... ignaling by mTORC1 and mTORC2.

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The kinase mTOR regulates the ...... ignaling by mTORC1 and mTORC2.

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Nature Immunology

P1476

The kinase mTOR regulates the ...... signaling by mTORC1 and mTORC2

@en

P2093

Adam T Waickman

http://www.w3.org/2001/XMLSchema#string

Bo Xiao

http://www.w3.org/2001/XMLSchema#string

David J Meyers

http://www.w3.org/2001/XMLSchema#string

Greg M Delgoffe

http://www.w3.org/2001/XMLSchema#string

Jonathan D Powell

http://www.w3.org/2001/XMLSchema#string

Kristen N Pollizzi

http://www.w3.org/2001/XMLSchema#string

Maureen R Horton

http://www.w3.org/2001/XMLSchema#string

Paul F Worley

http://www.w3.org/2001/XMLSchema#string

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation

Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.

mTOR regulates memory CD8 T-cell differentiation

SOCS-3 inhibits IL-12-induced STAT4 activation by binding through its SH2 domain to the STAT4 docking site in the IL-12 receptor beta2 subunit

Defining the role of mTOR in cancer

Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

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295-303

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scholarly article

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10.1038/NI.2005

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P433

4

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12

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Emily B Heikamp

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2011-02-27T00:00:00Z

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50227714

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21358638

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3077821

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