Shikonin kills glioma cells through necroptosis mediated by RIP-1
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Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapyAn outline of necrosome triggersThe role of necroptosis in neurosurgical diseasesThe anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.In vitro induction of erythrocyte phosphatidylserine translocation by the natural naphthoquinone shikonin.Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cellsColumbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells.N-end rule pathway inhibition assists colon tumor regression via necroptosis.Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species.Shikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian cancer.Harnessing of Programmed Necrosis for Fighting against Cancers.Shikonin induces necroptosis by reactive oxygen species activation in nasopharyngeal carcinoma cell line CNE-2Z.Cancer and necroptosis: friend or foe?Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal MedicineNecroptosis-inducing rhenium(V) oxo complexes.Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib.Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.RIP1 upregulation promoted tumor progression by activating AKT/Bcl-2/BAX signaling and predicted poor postsurgical prognosis in HCC.Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme.Exploitation of necroptosis for treatment of caspase-compromised cancers.Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation.Necrostatin-1 attenuates lipopolysaccharide-induced acute lung injury in mice.Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.
P2860
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P2860
Shikonin kills glioma cells through necroptosis mediated by RIP-1
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2013 nî lūn-bûn
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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
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2013年论文
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name
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@ast
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@en
Shikonin kills glioma cells through necroptosis mediated by RIP-1
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Shikonin kills glioma cells through necroptosis mediated by RIP-1
@ast
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@en
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@nl
prefLabel
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@ast
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@en
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@nl
P2093
P2860
P1433
P1476
Shikonin kills glioma cells through necroptosis mediated by RIP-1
@en
P2093
Chuanjiang Huang
Fuwei Yang
Hongwei Zhao
Jingwei Zhao
Pengfei Ge
Wenhai Fan
P2860
P304
P356
10.1371/JOURNAL.PONE.0066326
P407
P577
2013-06-28T00:00:00Z