Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis. - Wikidata - wikimedia - TriplyDB

Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.

Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.

http://www.wikidata.org/entity/Q34809359

about

Role of hyaluronan in pancreatic cancer biology and therapy: Once again in the spotlight The tumor microenvironment in esophageal cancer Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan The impact of the receptor of hyaluronan-mediated motility (RHAMM) on human urothelial transitional cell cancer of the bladder.4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.Increased hyaluronan levels in HABP1/p32/gC1qR overexpressing HepG2 cells inhibit autophagic vacuolation regulating tumor potency.Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis Inhibition of Hyaluronic Acid Synthesis Suppresses Angiogenesis in Developing Endometriotic Lesions.Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes.Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC).Binding of trastuzumab to ErbB2 is inhibited by a high pericellular density of hyaluronan.The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator-role of Ceramide in MU anti-tumor activity Esophageal Squamous Cell Carcinoma Cells Modulate Chemokine Expression and Hyaluronan Synthesis in Fibroblasts Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer.Targeting hyaluronic acid family for cancer chemoprevention and therapy.Sugars in the microenvironment: the sticky problem of HA turnover in tumors.Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen.The glycocalyx and its significance in human medicine.4-methylumbelliferone and imatinib combination enhances senescence induction in chronic myeloid leukemia cell lines.Synergistic effect of targeting the epidermal growth factor receptor and hyaluronan synthesis in oesophageal squamous cell carcinoma cells.Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice.FAK and HAS inhibition synergistically decrease colon cancer cell viability and affect expression of critical genes Hematopoiesis toxicity induced by 4-methylumbelliferon determined in an invertebrate model organism.Dietary supplement hymecromone and sorafenib: a novel combination for the control of renal cell carcinoma.Antioxidative properties of 4-methylumbelliferone are related to antibacterial activity in the silkworm (Bombyx mori) digestive tract.Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis.Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan.Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery.4-Methylumbelliferone inhibits enhanced hyaluronan synthesis and cell migration in pancreatic cancer cells in response to tumor-stromal interactions.Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

P2860

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P2860

Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.

http://www.wikidata.org/entity/Q34809359

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Inhibition of oesophageal squa ...... eting of hyaluronan synthesis.

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Inhibition of oesophageal squa ...... eting of hyaluronan synthesis.

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Molecular Cancer

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Inhibition of oesophageal squa ...... geting of hyaluronan synthesis

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Bernhard Homey

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Eva Poscher

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Frauke Alves

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Guang Dai

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Jens W Fischer

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Katharina Jannasch

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Klaus Prenzel

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Nikolas H Stoecklein

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Rashmin C Savani

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Till Freudenberger

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P2860

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

Global cancer statistics, 2002

Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

Prognostic value of hyaluronan expression in non-small-cell lung cancer: Increased stromal expression indicates unfavorable outcome in patients with adenocarcinoma.

Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells.

Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration.

Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells.

A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone.

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Christian Dullin

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50830614

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