Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. - Wikidata - wikimedia - TriplyDB

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

http://www.wikidata.org/entity/Q34825204

about

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation Mitochondria, cholesterol and cancer cell metabolism Cullin-RING ligases in regulation of autophagy Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance The Role of Autophagy in Hepatocellular Carcinoma Chloroquine and hydroxychloroquine for cancer therapy Mitophagy: mechanisms, pathophysiological roles, and analysis Autophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseases Autophagy in cellular metabolism and cancer Autophagy in malignant transformation and cancer progression Autophagy modulation as a potential therapeutic target for diverse diseases Role of p62/SQSTM1 in liver physiology and pathogenesis Targeting autophagy for the treatment of liver diseases Myc-driven overgrowth requires unfolded protein response-mediated induction of autophagy and antioxidant responses in Drosophila melanogaster p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming The multifaceted roles of autophagy in tumors-implications for breast cancer.Genetic alterations in hepatocellular carcinoma: An update Role of farnesoid X receptor and bile acids in alcoholic liver disease Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?Kaposi's sarcoma-associated herpesvirus induces Nrf2 activation in latently infected endothelial cells through SQSTM1 phosphorylation and interaction with polyubiquitinated Keap1 Regulation of Nrf2-an update The complexity of the Nrf2 pathway: beyond the antioxidant response The Keap1-Nrf2 system in cancers: stress response and anabolic metabolism p62 links autophagy and Nrf2 signaling The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?Cytoprotection "gone astray": Nrf2 and its role in cancer Bcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitro The p53-induced gene Ei24 is an essential component of the basal autophagy pathway Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma p62/SQSTM1 synergizes with autophagy for tumor growth in vivo.p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation.Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia.Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation.

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P2860

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

http://www.wikidata.org/entity/Q34825204

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@ast

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@en

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@nl

type

label

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@ast

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@en

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@nl

prefLabel

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@ast

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@en

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@nl

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P1433

Journal of Cell Biology

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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

@en

P2093

Ayako Sakamoto

http://www.w3.org/2001/XMLSchema#string

Jin Ando

http://www.w3.org/2001/XMLSchema#string

Kazuto Nakada

http://www.w3.org/2001/XMLSchema#string

Keiji Tanaka

http://www.w3.org/2001/XMLSchema#string

Manabu Iwadate

http://www.w3.org/2001/XMLSchema#string

Masayuki Yamamoto

http://www.w3.org/2001/XMLSchema#string

Myung-Shik Lee

http://www.w3.org/2001/XMLSchema#string

Okio Hino

http://www.w3.org/2001/XMLSchema#string

Satoshi Waguri

http://www.w3.org/2001/XMLSchema#string

Sumio Watanabe

http://www.w3.org/2001/XMLSchema#string

P2860

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Autophagy suppresses tumorigenesis through elimination of p62

P304

275-284

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scholarly article

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10.1083/JCB.201102031

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P407

P433

2

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P478

193

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Masaaki Komatsu

P577

2011-04-11T00:00:00Z

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51041510

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21482715

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3080263

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