Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomography
about
Nociceptin and the nociceptin receptor in learning and memoryChronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the ratBrain and whole-body imaging in rhesus monkeys of 11C-NOP-1A, a promising PET radioligand for nociceptin/orphanin FQ peptide receptors.Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors.A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models.Translational approach to develop novel medications on alcohol addiction: focus on neuropeptides.Measuring specific receptor binding of a PET radioligand in human brain without pharmacological blockade: The genomic plot.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.On quantitative relationships between drug-like compound lipophilicity and plasma free fraction in monkey and human.Brain and whole-body imaging of nociceptin/orphanin FQ peptide receptor in humans using the PET ligand 11C-NOP-1A.The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.Emerging targets for addiction neuropharmacology: From mechanisms to therapeuticsRetest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.Opioid system and Alzheimer's disease.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects.In-vivo rat striatal 5-HT4 receptor occupancy using non-radiolabelled SB207145.Nociceptin Receptors in Alcohol Use Disorders: A Positron Emission Tomography Study Using [11C]NOP-1A.Imaging corticotropin-releasing-factor and nociceptin in addiction and PTSD models.
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Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomography
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2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
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2011年論文
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2011年论文
@wuu
name
Synthesis and evaluation of ra ...... h positron emission tomography
@ast
Synthesis and evaluation of ra ...... h positron emission tomography
@en
Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide
@nl
type
label
Synthesis and evaluation of ra ...... h positron emission tomography
@ast
Synthesis and evaluation of ra ...... h positron emission tomography
@en
Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide
@nl
prefLabel
Synthesis and evaluation of ra ...... h positron emission tomography
@ast
Synthesis and evaluation of ra ...... h positron emission tomography
@en
Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide
@nl
P2093
P2860
P356
P1476
Synthesis and evaluation of ra ...... h positron emission tomography
@en
P2093
Concepción Pedregal
Jinsoo Hong
Johannes T Tauscher
Karen S Rash
Masahiro Fujita
Michael A Statnick
Miguel A Toledo
Nuria Diaz
Robert B Innis
Sami S Zoghbi
P2860
P304
P356
10.1021/JM101487V
P407
P577
2011-03-25T00:00:00Z