Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells
about
Rapamycin prevents the development and progression of mutant epidermal growth factor receptor lung tumors with the acquired resistance mutation T790M.MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways.Novel agents and strategies for overcoming EGFR TKIs resistance.EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer.Posttranslational modifications of FOXO1 regulate epidermal growth factor receptor tyrosine kinase inhibitor resistance for non-small cell lung cancer cells.γ Secretase inhibitor BMS-708163 reverses resistance to EGFR inhibitor via the PI3K/Akt pathway in lung cancer.Recent advances in targeting mTOR signaling pathway using small molecule inhibitors.Assessment of SRM, MRM(3) , and DIA for the targeted analysis of phosphorylation dynamics in non-small cell lung cancer.Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis.Phase I clinical trial of temsirolimus and vinorelbine in advanced solid tumors.The Role of Compounds Derived from Natural Supplement as Anticancer Agents in Renal Cell Carcinoma: A Review.Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells via mTOR activation through Akt-independent pathway.FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy.EGFR-TKI is effective regardless of treatment timing in pulmonary adenocarcinoma with EGFR mutation.
P2860
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P2860
Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@ast
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@en
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@nl
type
label
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@ast
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@en
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@nl
prefLabel
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@ast
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@en
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@nl
P2093
P2860
P1433
P1476
Targeting mTOR to overcome epi ...... n-small cell lung cancer cells
@en
P2093
Hai-Yu Zhou
Ling Huang
Shi-Jiang Fei
Xu-Chao Zhang
Yi-Fang Zhang
Yi-Long Wu
Zhi-Hong Chen
P2860
P304
P356
10.1371/JOURNAL.PONE.0069104
P407
P577
2013-07-16T00:00:00Z