A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms
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Insights into the nuclear export of murine leukemia virus intron-containing RNATetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus PathogenesisRetroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.Response and resistance to MEK inhibition in leukaemias initiated by hyperactive RasMyeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia.Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.GFI1B, EVI5, MYB--additional genes that cooperate with the human BCL6 gene to promote the development of lymphomasGenetic pathways leading to therapy-related myeloid neoplasms.Anaplastic plasmacytoma of mouse--establishing parallels between subtypes of mouse and human plasma cell neoplasia.Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2.PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomasSET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.Sox4 cooperates with CREB in myeloid transformationCytogenetic and genetic pathways in therapy-related acute myeloid leukemia.Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency.Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.Mutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns.Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice.Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.Novel insights into the pathogenesis of the Graffi murine leukemia retrovirus.Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo.Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice.Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation.
P2860
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P2860
A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
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2003年學術文章
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name
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@ast
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@en
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@nl
type
label
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@ast
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@en
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@nl
prefLabel
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@ast
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@en
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@nl
P2093
P2860
P1433
P1476
A Moloney murine leukemia viru ...... as well as lymphoid neoplasms
@en
P2093
Linda Wolff
Miriam R Anver
Richard Koller
Xinrong Hu
P2860
P304
P356
10.1128/JVI.77.8.4965-4971.2003
P407
P577
2003-04-01T00:00:00Z