Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
about
MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expressionMaster regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignanciesAnimal models of leukemia: any closer to the real thing?MicroRNAs in cancer.Orthologous microRNA genes are located in cancer-associated genomic regions in human and mouseGene profiling of the erythro- and megakaryoblastic leukaemias induced by the Graffi murine retrovirus.Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.Mouse models of myelodysplastic syndromes.Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia.Mapping of MN1 sequences necessary for myeloid transformation.Cancer gene discovery in mouse and man.Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia.NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insightsAssociation between microRNA196a2 rs11614913 genotypes and the risk of non-small cell lung cancer in Korean population.PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomasAn insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.Sox4 cooperates with CREB in myeloid transformationThree murine leukemia virus integration regions within 100 kilobases upstream of c-myb are proximal to the 5' regulatory region of the gene through DNA looping.Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice.Identifying candidate genes involved in brain tumor formation.Identification of Hematopoietic Stem Cell Engraftment Genes in Gene Therapy Studies.Update on cytogenetic and molecular changes in myelodysplastic syndromes.Molecular mechanism of microRNA involvement in genesis of myelodysplastic syndrome and its transformation to acute myeloid leukemia.Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling.NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia.Standardization of flow cytometry in myelodysplastic syndromes: report from the first European LeukemiaNet working conference on flow cytometry in myelodysplastic syndromes.The Meningioma 1 (MN1) Gene is an Independent Poor Prognostic Factor in Adult Egyptian Acute Myeloid Leukemia PatientsAssociation between genetic variants in pre-miRNA and colorectal cancer risk in a Chinese population.Transcriptional deregulation of oncogenic myocyte enhancer factor 2C in T-cell acute lymphoblastic leukemia.Genetic variants in miR-146a, miR-149, miR-196a2, miR-499 and their influence on relative expression in lung cancers.A variant in microRNA-196a2 is not associated with susceptibility to and progression of colorectal cancer in Chinese.
P2860
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P2860
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Retroviral insertional mutagen ...... uring leukemic transformation.
@en
Retroviral insertional mutagen ...... uring leukemic transformation.
@nl
type
label
Retroviral insertional mutagen ...... uring leukemic transformation.
@en
Retroviral insertional mutagen ...... uring leukemic transformation.
@nl
prefLabel
Retroviral insertional mutagen ...... uring leukemic transformation.
@en
Retroviral insertional mutagen ...... uring leukemic transformation.
@nl
P2093
P2860
P1433
P1476
Retroviral insertional mutagen ...... during leukemic transformation
@en
P2093
Helge Hartung
Juraj Bies
Linda Wolff
Peter D Aplan
Ying-Wei Lin
P2860
P304
P356
10.1158/0008-5472.CAN-07-0075
P407
P577
2007-06-01T00:00:00Z