Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles. - Wikidata - wikimedia - TriplyDB

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.

http://www.wikidata.org/entity/Q34869120

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Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism The spectrum of disease in chronic traumatic encephalopathy Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds Is tau ready for admission to the prion club?Untangling tau imaging Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles Insights into Mechanisms of Chronic Neurodegeneration Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing Problem The role of tau in neurodegenerative diseases and its potential as a therapeutic target Proteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson disease Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models Induced tauopathy in a novel 3D-culture model mediates neurodegenerative processes: a real-time study on biochips The preclinical phase of the pathological process underlying sporadic Alzheimer's disease The Glymphatic System: A Beginner's Guide Alzheimer's disease and prion protein The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease Distinct α-synuclein strains differentially promote tau inclusions in neurons The release and trans-synaptic transmission of Tau via exosomes Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury Alzheimer disease: a tale of two prions Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.Biomarkers in the Diagnosis and Prognosis of Alzheimer's Disease.The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin.Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.A high-throughput screening assay for determining cellular levels of total tau protein.Glial contributions to neurodegeneration in tauopathies.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Biology and genetics of prions causing neurodegeneration Acetylation: a new key to unlock tau's role in neurodegeneration Single mutations in tau modulate the populations of fibril conformers through seed selection.Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injury Proteopathic tau seeding predicts tauopathy in vivo.Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits

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P2860

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.

http://www.wikidata.org/entity/Q34869120

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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type

label

Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

@ast

Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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JBC.M110.209296

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Journal of Biological Chemistry

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Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.

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Jing L Guo

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Virginia M-Y Lee

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P2860

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

Transmission and spreading of tauopathy in transgenic mouse brain

Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates

Neuropathological stageing of Alzheimer-related changes

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

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15317-15331

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Alzheimer's disease

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3083182

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