Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.
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Hydrogen peroxide - production, fate and role in redox signaling of tumor cellsWood Smoke Particle Sequesters Cell Iron to Impact a Biological EffectCellular iron depletion and the mechanisms involved in the iron-dependent regulation of the growth arrest and DNA damage family of genesQuantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugsIron and cancer: more ore to be mined.CrMAPK3 regulates the expression of iron-deficiency-responsive genes in Chlamydomonas reinhardtiip38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytesRole of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade.Novel immunosuppressive agent caerulomycin A exerts its effect by depleting cellular iron contentProtein carbonylation and metabolic control systems.Targeting cancer by binding iron: Dissecting cellular signaling pathwaysIron mitigates DMT1-mediated manganese cytotoxicity via the ASK1-JNK signaling axis: Implications of iron supplementation for manganese toxicity.Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents.Iron increases the susceptibility of multiple myeloma cells to bortezomib.Role of p38 MAP Kinase Signal Transduction in Solid TumorsMolecular mechanisms of cognitive impairment in iron deficiency: alterations in brain-derived neurotrophic factor and insulin-like growth factor expression and function in the central nervous system.The Iron Chelator, Dp44mT, Effectively Inhibits Human Oral Squamous Cell Carcinoma Cell Growth in Vitro and in Vivo.Iron Status Is Associated with Performance on Executive Functioning Tasks in Nonanemic Young Women.Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms.Delayed cell cycle progression in selenoprotein W-depleted cells is regulated by a mitogen-activated protein kinase kinase 4-p38/c-Jun NH2-terminal kinase-p53 pathway.Bacterial cell wall constituents induce hepcidin expression in macrophages through MyD88 signaling.The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.Iron chelation: deciphering novel molecular targets for cancer therapy. The tip of the iceberg of a web of iron-regulated molecules.Asthma as a disruption in iron homeostasis.Fine-tuned iron availability is essential to achieve optimal adipocyte differentiation and mitochondrial biogenesis.Sequestration of mitochondrial iron by silica particle initiates a biological effect.Suberoylanilide hydroxamic acid induces thioredoxin1-mediated apoptosis in lung cancer cells via up-regulation of miR-129-5p.Vitamin D enhances omega-3 polyunsaturated fatty acids-induced apoptosis in breast cancer cells.Cell cycle arrest and apoptosis induced by Porphyromonas gingivalis requires JNK- and p53-mediated p38 activation in human trophoblasts.Iron induces hepatocytes death via MAPK activation and mitochondria-dependent apoptotic pathway: beneficial role of glycine.
P2860
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P2860
Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@ast
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@en
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@nl
type
label
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@ast
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@en
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@nl
prefLabel
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@ast
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@en
Cellular iron depletion stimul ...... doxin, and activation of ASK1.
@nl
P2860
P356
P1476
Cellular iron depletion stimul ...... edoxin, and activation of ASK1
@en
P2093
Des R Richardson
P2860
P304
15413-15427
P356
10.1074/JBC.M111.225946
P407
P577
2011-03-05T00:00:00Z