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Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.Tuning cell cycle regulation with an iron key.Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.The medicinal chemistry of novel iron chelators for the treatment of cancer.Melanotransferrin: search for a function.Iron chelators for the treatment of cancer.Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity.Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer.Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosisChelators to the Rescue: Different Horses for Different Courses!Ovarian cancer stem cells and their role in drug resistancePericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisionsProteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian TumorsTherapeutic Inducers of Apoptosis in Ovarian CancerMechanisms underlying acquired platinum resistance in high grade serous ovarian cancer - a mini reviewSpleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancerInactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-0209-0586
@en
name
Yu Yu
@ast
Yu Yu
@en
Yu Yu
@nl
type
label
Yu Yu
@ast
Yu Yu
@en
Yu Yu
@nl
prefLabel
Yu Yu
@ast
Yu Yu
@en
Yu Yu
@nl
P108
P106
P31
P496
0000-0002-0209-0586