A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure
about
Personalized medicine: hope or hype?Pharmacogenetics of beta-blockersCardiovascular pharmacogenomics: current status and future directionsPharmacogenetics in chronic heart failure: new developments and current challengesPharmacogenetics and anaesthesia: the value of genetic profilingClinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementationPharmacogenomics of hypertension and heart diseaseCrystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and CarvedilolCombinatorial pharmacogenetic interactions of bucindolol and β1, α2C adrenergic receptor polymorphismsReal-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilolDistinct and Shared Determinants of Cardiomyocyte Contractility in Multi-Lineage Competent Ethnically Diverse Human iPSCs.Arg389Gly β1-adrenergic receptor polymorphism and susceptibility to syncope during tilt testMultiple interactions between the alpha 2C- and beta1-adrenergic receptors influence heart failure survival.Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation.G protein-coupled receptors in cardiac biology: old and new receptorsThe Genetic Challenges and Opportunities in Advanced Heart FailurePharmacogenomics of beta1-adrenergic receptor polymorphisms in heart failure.Genomics, heart failure and sudden cardiac death.Beta-blocker pharmacogenetics in heart failure.GNAS gene variants affect β-blocker-related survival after coronary artery bypass grafting.Applied pharmacogenomics in cardiovascular medicineReduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarctionβ1 adrenergic receptor polymorphisms and heart failure: a meta-analysis on susceptibility, response to β-blocker therapy and prognosisRAAS and adrenergic genes in heart failure: Function, predisposition and survival implicationsEmerging clinical applications in cardiovascular pharmacogenomics.Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization.Pharmacogenetic effect of an endothelin-1 haplotype on response to bucindolol therapy in chronic heart failureBeta 1- and beta 2-adrenoceptor polymorphisms and cardiovascular diseases.{beta}-Adrenoceptor gene variation and intermediate physiological traits: prediction of distant phenotypeG protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockersMicroRNA let-7 establishes expression of beta2-adrenergic receptors and dynamically down-regulates agonist-promoted down-regulation.Association of beta-adrenergic receptor polymorphisms and mortality in carvedilol-treated chronic heart-failure patientsPharmacogenomics: the genetics of variable drug responses.Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy.Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individualsCardiovascular pharmacogenomics and individualized drug therapyCardiovascular pharmacogenomics of adrenergic receptor signaling: clinical implications and future directionsThe genomic architecture of sporadic heart failureImpact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor.Strategic approaches to unraveling genetic causes of cardiovascular diseases.
P2860
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P2860
A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A polymorphism within a conserved beta
@nl
A polymorphism within a conser ...... esponse in human heart failure
@ast
A polymorphism within a conser ...... esponse in human heart failure
@en
type
label
A polymorphism within a conserved beta
@nl
A polymorphism within a conser ...... esponse in human heart failure
@ast
A polymorphism within a conser ...... esponse in human heart failure
@en
prefLabel
A polymorphism within a conserved beta
@nl
A polymorphism within a conser ...... esponse in human heart failure
@ast
A polymorphism within a conser ...... esponse in human heart failure
@en
P2093
P2860
P356
P1476
A polymorphism within a conser ...... esponse in human heart failure
@en
P2093
Bradley Nelson
Danielle Hodne
Heidi J Krause-Steinrauf
J David Port
Jeffrey L Anderson
Jennifer Morrison
John F Carlquist
Lynne E Wagoner
Michael J Domanski
Michael R Bristow
P2860
P304
11288-11293
P356
10.1073/PNAS.0509937103
P407
P577
2006-07-14T00:00:00Z