Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.
about
Phase I/Ib study of olaparib and carboplatin in BRCA1 or BRCA2 mutation-associated breast or ovarian cancer with biomarker analyses.Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancerRibavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia.The oncogene eIF4E: using biochemical insights to target cancer.Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.Expression of phosphorylated eIF4E-binding protein 1, but not of eIF4E itself, predicts survival in male breast cancerPhosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells.mRNA export and cancer.Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation.Using antimicrobial adjuvant therapy in cancer treatment: a review.Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond.The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Targeting translation: eIF4E as an emerging anticancer drug target.The effects of antiviral treatment on breast cancer cell line.Translational control of the fibroblast-extracellular matrix association: An application to pulmonary fibrosis.Efficacy of ribavirin against malignant glioma cell lines.RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.Identification of drug candidate against prostate cancer from the aspect of somatic cell reprogramming.Targeting of protein translation as a new treatment paradigm for prostate cancer.The eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions.Anti-tumor effect of ribavirin in combination with interferon-α on renal cell carcinoma cell lines in vitro.Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia.Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.The ABC7 regimen: a new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy.Comparison between Platinum-Azidothymidine and Azidothymidine Effects on Bcl-2 and Telomerase Gene Expression in Rats with Hepatocellular CarcinomaPharmacological targeting of eIF4E in primary CLL lymphocytes.Inducible drug modification: a new form of resistance.Targeted Dual pH-Sensitive Lipid ECO/siRNA Self-Assembly Nanoparticles Facilitate In Vivo Cytosolic sieIF4E Delivery and Overcome Paclitaxel Resistance in Breast Cancer Therapy.Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment.The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity.Inhibition of eIF4E cooperates with chemotherapy and immunotherapy in renal cell carcinoma.Ribavirin augments doxorubicin's efficacy in human hepatocellular carcinoma through inhibiting doxorubicin-induced eIF4E activation.Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors.RAS/MAPK pathway hyperactivation determines poor prognosis in undifferentiated pleomorphic sarcomas.The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner.Expression of 4E-BP1 and phospho-4E-BP1 correlates with the prognosis of patients with clear cell renal carcinoma.
P2860
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P2860
Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@ast
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@en
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@nl
type
label
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@ast
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@en
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@nl
prefLabel
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@ast
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@en
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@nl
P2093
P2860
P1476
Ribavirin treatment effects on ...... luminal B-type breast cancer.
@en
P2093
Biljana Culjkovic-Kraljacic
Caroline Rousseau
Christina Yau
Christopher C Benz
Eftihia Cocolakis
Filippa Pettersson
Hélène Retrouvey
Ian E Krop
Katherine L B Borden
Ludmila M Flores
P2860
P304
P356
10.1158/1078-0432.CCR-10-2334
P407
P577
2011-03-17T00:00:00Z