Location of the retinal chromophore in the activated state of rhodopsin*.
about
Overexpression of membrane proteins in mammalian cells for structural studiesThe structural basis of agonist-induced activation in constitutively active rhodopsinStabilized G protein binding site in the structure of constitutively active metarhodopsin-IIUnderstanding functional residues of the cannabinoid CB1.Structural approaches to understanding retinal proteins needed for visionRetinal conformation governs pKa of protonated Schiff base in rhodopsin activationHydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.Molecular dynamics simulations reveal specific interactions of post-translational palmitoyl modifications with rhodopsin in membranes.Structures of membrane proteins.Molecular simulations and solid-state NMR investigate dynamical structure in rhodopsin activation.G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy.Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structuresMicrosecond time-resolved circular dichroism of rhodopsin photointermediates.Structure and function of G protein-coupled receptors using NMR spectroscopy.Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region.Highly conserved tyrosine stabilizes the active state of rhodopsin.Coupling of retinal, protein, and water dynamics in squid rhodopsin.Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsinSolid-state NMR study of the charge-transfer complex between ubiquinone-8 and disulfide bond generating membrane protein DsbBUncovering the triggers for GPCR activation using solid-state NMR spectroscopy.Evidence from Chlamydomonas on the photoactivation of rhodopsins without isomerization of their chromophore.Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation.6-s-cis Conformation and polar binding pocket of the retinal chromophore in the photoactivated state of rhodopsinRetinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy.Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation.CONDENSED-MATTER SPECTROSCOPY SPECTRAL METHODS FOR STUDY OF THE G-PROTEIN-COUPLED RECEPTOR RHODOPSIN. II. MAGNETIC RESONANCE METHODS.Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.Conserved activation pathways in G-protein-coupled receptors.Insights into the activation mechanism of the visual receptor rhodopsin.Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.A pivot between helices V and VI near the retinal-binding site is necessary for activation in rhodopsins.Retinal Conformation Changes Rhodopsin's Dynamic Ensemble.Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.The importance of valine 114 in ligand binding in beta(2)-adrenergic receptor.Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptorSalt effects on the conformational stability of the visual G-protein-coupled receptor rhodopsin.Structural transitions of transmembrane helix 6 in the formation of metarhodopsin I.A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors.Retinal Flips the Script.Retinal Flip in Rhodopsin Activation?
P2860
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P2860
Location of the retinal chromophore in the activated state of rhodopsin*.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Location of the retinal chromophore in the activated state of rhodopsin*.
@ast
Location of the retinal chromophore in the activated state of rhodopsin*.
@en
Location of the retinal chromophore in the activated state of rhodopsin*.
@nl
type
label
Location of the retinal chromophore in the activated state of rhodopsin*.
@ast
Location of the retinal chromophore in the activated state of rhodopsin*.
@en
Location of the retinal chromophore in the activated state of rhodopsin*.
@nl
prefLabel
Location of the retinal chromophore in the activated state of rhodopsin*.
@ast
Location of the retinal chromophore in the activated state of rhodopsin*.
@en
Location of the retinal chromophore in the activated state of rhodopsin*.
@nl
P2093
P2860
P356
P1476
Location of the retinal chromophore in the activated state of rhodopsin*.
@en
P2093
Amiram Hirshfeld
Evan Crocker
H Gobind Khorana
Markus Eilers
Martine Ziliox
Mordechai Sheves
Natalie Syrett
Philip J Reeves
Shivani Ahuja
Steven O Smith
P2860
P304
10190-10201
P356
10.1074/JBC.M805725200
P407
P577
2009-01-28T00:00:00Z